Ceritinib Impurity 24 CAS CATO-C4X-104824
| CAS No. | CATO-C4X-104824 |
| Molecular Formula | C13H13Cl2N3S |
| Molecular Weight | 314.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Ceritinib Impurity 24 (C13H13Cl2N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 314.23 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Ceritinib Impurity 24 (CAS CATO-C4X-104824) is a certified pharmaceutical impurity reference standard with the molecular formula C13H13Cl2N3S and a molecular weight of 314.23 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ceritinib Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H13Cl2N3S |
| Molecular Weight | 314.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ceritinib Standards
- Ceritinib Impurity 16 (CAS CATO-C4X-104816)
- Ceritinib Impurity 22 (CAS CATO-C4X-104822)
- Ceritinib Impurity 23 (CAS CATO-C4X-104823)
- Ceritinib Impurity 18 (CAS CATO-C4X-1048918)
- Ceritinib Impurity 82 (CAS CATO-C4X-104882)
- Ceritinib Impurity 17 (CAS CATO-C4X-104817)
- Ceritinib Impurity 1 (CAS CATO-C4X-10481)
- Ceritinib Impurity 83 (CAS CATO-C4X-104883)
Recommended Standards
- 2-Bromo-1-(3,4-dihydro-2h-1,4-benzothiazin-4-yl)-3-methylbutan-1-one (CAS 1097794-82-5)
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- Diphenyl(3,3,3-trifluoro-2-hydroxypropyl)phosphine oxide (CAS 123271-28-3)
- N-(3,5-Bis(trifluoromethyl)phenyl)(propylamino)formamide (CAS 23751-81-7)
- Ubenimex Impurity 5 (CAS 118943-10-5)
- Valganciclovir Impurity C17 HCI (CAS 1654737-32-2)
- Pazopanib Impurity 30 (CAS 1313372-75-6)
- 3-Hydroxy-4-methylpyridine (CAS 1121-19-3)
- 2-Chloro-benzeneacetaldehyde (CAS 4251-63-2)
- 3-(Trimethylsilyl)propionic Acid-d4 Sodium Salt (CAS 24493-21-8)
- 6-Chloronaphthalene-1-carboxylic acid (CAS 16650-53-6)
- 5-Bromo-N-methyl-N-(2-oxo-2-(propylamino)ethyl)nicotinamide (CAS 924723-32-0)
- 3-Bromo-4,6-dichloro-1H-indazole (CAS 887568-12-9)
- Peptide YY (human) trifluoroacetate salt (CAS 118997-30-1)
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