Sofosbuvir Impurity 63 CAS CATO-C4X-105263
| CAS No. | CATO-C4X-105263 |
| Molecular Formula | C16H18FN2O8P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Sofosbuvir Impurity 63 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Sofosbuvir Impurity 63 (CAS CATO-C4X-105263), a pharmacopoeial impurity reference standard (molecular formula C16H18FN2O8P·1/6(C7H15NO), MW 545.50 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution, Sofosbuvir Impurity 63 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 545.50 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C16H18FN2O8P · 1/6 (C7H15NO) |
| Molecular Weight | 545.50 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Sofosbuvir Standards
- Sofosbuvir Impurity 70 (CAS 10065-72-2)
- Sofosbuvir Impurity 109 (CAS 10113-28-7)
- Sofosbuvir Impurity 50 (CAS 1015073-43-4)
- Sofosbuvir Impurity 1 (CAS 1033394-94-3)
- Sofosbuvir O-Desisopropyl O-Ethyl Ester (CAS 1064684-30-5)
- Sofosbuvir Impurity 98 (CAS 111955-47-6)
- Sofosbuvir Impurity 12 (CAS 114262-49-6)
- Sofosbuvir Impurity 2 (CAS 1157884-58-6)
Recommended Standards
- Oseltamivir Impurity 216 (CAS CATO-C4X-1720216)
- Gadoxetate Impurity 4 Gadolinium(III) Disodium salt (CAS CATO-C4X-26184)
- Ziprasidone Impurity 40 (CAS CATO-C4X-124040)
- Tirofiban Impurity 117 (CAS CATO-C4X-1254117)
- (2Z)-N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}ethyl)-3-[(4-methoxyphenyl)amino]-N-methyl-2-phenylprop-2-enamide (CAS 337919-79-6)
- 2-(5-((2,4-Dichlorophenoxy)methyl)-1,2,4-oxadiazol-3-yl)-N-methylethan-1-amine (CAS 1160245-37-3)
- DIethyl isopropenyl phosphate (CAS 5954-28-9)
- tert-Butyl 1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxylate (CAS 1023595-11-0)
- 2-(chloromethyl)-1-methoxy-4-methylbenzene (CAS 7048-41-1)
- Insulin Degludec Impurity 14 (CAS CATO-C4X-215714)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com