Sofosbuvir Impurity 64 CAS CATO-C4X-105264
| CAS No. | CATO-C4X-105264 |
| Molecular Formula | C16H25FN3O9P |
| Molecular Weight | 453.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Sofosbuvir Impurity 64 (CAS CATO-C4X-105264), a pharmacopoeial impurity reference standard (molecular formula C16H25FN3O9P, MW 453.36 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Sofosbuvir Impurity 64 (C16H25FN3O9P) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Sofosbuvir Impurity 64 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H25FN3O9P |
| Molecular Weight | 453.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Sofosbuvir Standards
- Sofosbuvir Impurity N40 (CAS 1256490-52-4)
- Sofosbuvir Impurity 120 (CAS 2190510-88-2)
- Sofosbuvir Impurity 39 (CAS 1496551-91-7)
- Sofosbuvir Impurity 57 (CAS 1337529-56-2)
- Sofosbuvir Impurity 58 (CAS 1714114-25-6)
- Sofosbuvir Impurity 59 (CAS 1627824-09-2)
- Sofosbuvir Impurity 70 (CAS 1334513-02-8)
- Sofosbuvir Impurity 87 (CAS 157037-56-4)
Recommended Standards
- 3-[2-Cyano-3-(trifluoromethyl)phenoxy]phenyl 4,4,4-Trifluorobutane-1-sulfonate (CAS 406205-74-1)
- 5-(4-Bromophenyl)-2-((4-fluorobenzyl)thio)-1-(p-tolyl)-1H-imidazole (CAS 1206998-32-4)
- O-Desphenyl Sofosbuvir (CAS 1233335-82-4)
- 2-((9,10-Dioxo-9,10-dihydroanthracen-2-yl)amino)-2-oxoethyl 4-(trifluoromethyl)benzoate (CAS 867157-14-0)
- Phenytoin Impurity 22 (CAS CATO-C4X-186422)
- Fluticasone Impurity 105 (CAS CATO-C4X-1650105)
- Prochlorperazine EP Impurity A (CAS 10078-27-0)
- 4-Ethylbenzo[d]oxazole-2-acetic acid (CAS 1804188-66-6)
- 1-(2-Methylpropyl)-1H-pyrazole-5-carbaldehyde (CAS 1236366-12-3)
- Estradiol Impurity 4 (CAS 566-75-6)
- 3-Phenylbicyclo[1.1.1]pentan-1-amine (CAS 784093-32-9)
- (Z)-4-Benzylidene-3-(phenoxymethyl)isoxazol-5(4H)-one (CAS 112082-71-0)
- 2-Nitrophenol (CAS 88-75-5)
- Eledoisin Related Peptide (CAS 2990-43-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com