Sofosbuvir Impurity 94 CAS CATO-C4X-105294
| CAS No. | CATO-C4X-105294 |
| Molecular Formula | C20H25FN3O9P |
| Molecular Weight | 501.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Sofosbuvir Impurity 94 is closely related to a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Sofosbuvir Impurity 94 (CAS CATO-C4X-105294) is a certified pharmaceutical impurity reference standard with the molecular formula C20H25FN3O9P and a molecular weight of 501.40 g/mol.
Structurally, Sofosbuvir Impurity 94 (C20H25FN3O9P) contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.5, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 501.40 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Sofosbuvir Impurity 94 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H25FN3O9P |
| Molecular Weight | 501.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Sofosbuvir Standards
- Sofosbuvir Impurity 89 (CAS 1394157-34-6)
- Sofosbuvir Impurity 107 (CAS CATO-C4X-1052107)
- Sofosbuvir Impurity 62 (CAS CATO-C4X-105262)
- Sofosbuvir O-Desisopropyl O-Ethyl Ester (CAS 1064684-30-5)
- Sofosbuvir Impurity 17 (CAS 1496551-71-3)
- Sofosbuvir Impurity 98 (CAS CATO-C4X-105298)
- Sofosbuvir Impurity 92 (CAS CATO-C4X-105292)
- Sofosbuvir Impurity 95 (CAS 7392-74-7)
Recommended Standards
- N-(3-(4-Bromophenyl)-1-(4-phenylthiazol-2-yl)-1H-pyrazol-5-yl)benzamide (CAS 74101-27-2)
- Tobramycin Impurity 15 (CAS 207670-58-4)
- 4-((2,4-Dichloro-5-methoxyphenyl)amino)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinoline-3-carbonitrile (CAS 622368-91-6)
- Carprofen Impurity 2 (CAS CATO-C4X-30342)
- Cefazedone Impurity 5 (CAS CATO-C4X-11715)
- Ursodeoxycholic Acid impurity 72 (CAS 2168516-46-7)
- Teneligliptin Impurity 14 (CAS CATO-C4X-176014)
- N-(PEG3-acid)-N-bis(PEG3-amine) (CAS 2183440-35-7)
- 3-(3,5-Dimethyl-1-phenyl-1h-pyrazol-4-yl)propanoic acid (CAS 381697-36-5)
- 3-(Aminomethyl)-3-(p-tolyl)cyclobutan-1-ol (CAS 1486451-88-0)
- 2-Azido-2-deoxy-D-galacturonate 1,3,4-Triacetate Methyl Ester (CAS 81997-92-4)
- 1-(3,4-Diethylphenyl)ethan-1-one (CAS 102405-35-6)
- CREATINOL-O-PHOSPHATE (CAS 6903-79-3)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com