Sofosbuvir Impurity 95 CAS CATO-C4X-105295
| CAS No. | CATO-C4X-105295 |
| Molecular Formula | C18H29N2O6P |
| Molecular Weight | 400.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, Sofosbuvir Impurity 95 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 400.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Sofosbuvir Impurity 95 (CAS CATO-C4X-105295, C18H29N2O6P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Sofosbuvir Impurity 95 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H29N2O6P |
| Molecular Weight | 400.41 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Sofosbuvir Standards
- Sofosbuvir Impurity 85 (CAS 1621160-31-3)
- Sofosbuvir Impurity 51 (CAS 1233335-78-8)
- Sofosbuvir Impurity 68 (CAS 1496551-65-5)
- Sofosbuvir Impurity 89 (CAS CATO-C4X-105289)
- Sofosbuvir Impurity 97 (CAS 1911578-88-5)
- Sofosbuvir Impurity 84 (CAS 914912-69-9)
- Sofosbuvir Impurity 1 (CAS 1033394-94-3)
- Sofosbuvir Impurity 105 (CAS 1946820-91-2)
Recommended Standards
- N-(4-((3,5-Dimethyl-1H-pyrazol-1-yl)sulfonyl)phenyl)-3-nitrobenzamide (CAS 89565-54-8)
- tert-Butyl N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-N-[3-(trifluoromethyl)phenyl]carbamate (CAS 1208410-26-7)
- N-(2,5-dimethoxyphenyl)-3-(2-nitrophenoxy)thiophene-2-carboxamide (CAS 252027-02-4)
- GO-Y078 (CAS 1217503-60-0)
- Bilastine Impurity 12 HCl (CAS 2099128-83-1(Free base))
- Huperzine A Impurity 8 (CAS CATO-C4X-31238)
- Furosemide Impurity 25 (CAS CATO-C4X-140235)
- 1-[6-Chloro-2-(trifluoromethyl)quinol-4-yl]homopiperazine (CAS 541539-68-8)
- 6-(Benzylthio)-9-methyl-9H-purine (CAS 91803-89-3)
- 3-chloro-2-(chloromethyl)-4-methylquinoline hydrochloride (CAS 1009306-54-0)
- Ethyl 2-(4-bromo-3,5-dimethyl-1H-pyrazol-1-yl)acetate (CAS 175137-54-9)
- 5-(2-thiazol-2-ylethynyl)-1,2-benzoxazol-3-amine (CAS 2493791-35-6)
- 1,2,3,4-Tetrahydronaphthalene-1-carboximidamide (CAS 1339547-74-8)
- (Glu1)-Fibrinopeptide B (human) (CAS 103213-49-6)
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