Bromhexine EP Impurity D(HCl) CAS CATO-C4X-106016
| CAS No. | CATO-C4X-106016 |
| Molecular Formula | C14H21BrN2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 333.70 g/mol gives Bromhexine EP Impurity D(HCl) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Bromhexine EP Impurity D(HCl) (CAS CATO-C4X-106016, C14H21BrN2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Bromhexine EP Impurity D(HCl) (C14H21BrN2HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Bromhexine EP Impurity D(HCl) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H21BrN2 HCl |
| Molecular Weight | 333.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromhexine Standards
- Bromhexine Impurity 35 (CAS 100-60-7)
- Bromhexine impurity 59 (CAS 100669-81-6)
- Bromhexine Impurity 51 (CAS 100669-82-7)
- Bromhexine EP Impurity D(2HCl) (CAS 10076-98-9)
- Bromhexine Impurity 22 (CAS 114059-99-3)
- Bromhexine Impurity 17 (CAS 114390-40-8)
- Bromhexine Impurity N3 (CAS 114390-41-9)
- Bromhexine impurity 60 (CAS 1261676-18-9)
Recommended Standards
- Canagliflozin Impurity 86 (CAS CATO-C4X-112386)
- Atosiban Impurity 90 (CAS 125814-33-7)
- Difelikefalin Impurity 72 (CAS CATO-C4X-304172)
- (3R,4R)-rel-tert-Butyl 3-fluoro-4-(hydroxymethyl)piperidine-1-carboxylate (CAS 882033-94-5)
- 4'-[({[(2Z)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylidene]amino}oxy)methyl]-[1,1'-biphenyl]-2-carbonitrile (CAS 946386-30-7)
- 1-Acetyl-4-nitrosopiperazine (CAS 73742-56-0)
- (2,6-Dichloro-2,4-difluoro-[1,1-biphenyl]-4-yl)methanol (CAS 1350760-19-8)
- 2-(3-(Isopropyl(methyl)amino)piperidin-1-yl)ethanol (CAS 1353975-06-0)
- N4-[3-methoxy-5-(trifluoromethyl)phenyl]-5-chloro-1,3-dimethyl-1H-pyrazole-4-sulphonamide (CAS 648408-34-8)
- Atrial Natriuretic Polypeptide (4-28), human (CAS 95896-08-5)
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