Bromhexine impurity 61 CAS CATO-C4X-106061
| CAS No. | CATO-C4X-106061 |
| Molecular Formula | C16H21Br2N3O3 |
| Molecular Weight | 463.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Bromhexine impurity 61 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Bromhexine impurity 61 (CAS CATO-C4X-106061), a pharmacopoeial impurity reference standard (molecular formula C16H21Br2N3O3, MW 463.16 g/mol) used for the identification and quantification of trace impurities in APIs.
Bromhexine impurity 61 (C16H21Br2N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C16H21Br2N3O3 |
| Molecular Weight | 463.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Bromhexine Standards
- Bromhexine impurity 53 (CAS CATO-C4X-106053)
- Bromhexine Impurity 18 (CAS CATO-C4X-106018)
- Bromhexine Impurity 47 (CAS CATO-C4X-106047)
- Bromhexine impurity 54 (CAS CATO-C4X-106054)
- Bromhexine impurity 55 (CAS CATO-C4X-106055)
- Bromhexine Impurity 15 (CAS 2724689-57-8)
- Bromhexine Impurity 44 (CAS CATO-C4X-106044)
- Bromhexine Impurity 20 (CAS CATO-C4X-106020)
Recommended Standards
- 2,4-Dibromo-1-(cyclohexylamino)anthracene-9,10-dione (CAS 139488-56-5)
- N,N-bis(4-bromophenyl)-2,4-dimethoxyaniline (CAS 1450934-13-0)
- 5-Bromo-1-(phenylsulfonyl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 1357387-25-7)
- 1024280-79-2 2-(3-bromophenyl)-1-(3,4-dichlorophenyl)-6,6-dimethyl-4,5,6,7-tetrahydro-1H-indol-4-one MS-10299 (CAS 1024280-79-2)
- Trelagliptin Impurity 31 (CAS CATO-C4X-104631)
- Ceftazidime Impurity 31 (CAS CATO-C4X-121231)
- Rotigotine EP Impurity B Hydrochloride (CAS 101470-23-9（free base）)
- 5-((Benzyloxy)carbonyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylic acid (CAS 1265893-86-4)
- 4-Chloro-3-(difluoromethyl)-5-(hydroxymethyl)picolinonitrile (CAS 1804666-57-6)
- (4-(2-Fluoropropan-2-yl)pyrimidin-5-yl)methanamine (CAS 1427195-33-2)
- 3-(Cyanomethyl)-5-(difluoromethyl)-4-methoxypicolinonitrile (CAS 1805378-72-6)
- 6-(2,2,2-Trifluoroethyl)pyridin-3-ol (CAS 1346531-74-5)
- 108375-77-5 PC 766B Oxacyclohexadeca-3,5,11,13-tetraen-2-one, 16-((1S,2R,3S)-3-((2R,4R,5S,6R)-4-((2,6-dideoxy-beta-D-arabino-hexopyranosyl)oxy)tetrahydro-2-hydroxy-5-methyl-6-((1E,3E)-1,3-pentadienyl)-2H-pyran-2-yl)-2-hydroxy-1-methylbutyl)-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-, (3Z,5E,7R,8S,9S,11E,13E,15S,16R)- PC-766B (CAS 108375-77-5)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com