Edoxaban Impurity 127 CAS CATO-C4X-1063127
| CAS No. | CATO-C4X-1063127 |
| Molecular Formula | C25H33ClN7O4S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Edoxaban Impurity 127.
Edoxaban Impurity 127 (CAS CATO-C4X-1063127) is a certified pharmaceutical impurity reference standard with the molecular formula C25H33ClN7O4SI and a molecular weight of 689.99 g/mol.
Structurally, Edoxaban Impurity 127 (C25H33ClN7O4SI) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 689.99 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Edoxaban Impurity 127 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H33ClN7O4S I |
| Molecular Weight | 689.99 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Edoxaban Standards
- Edoxaban Impurity 73 (CAS 1057651-37-2)
- Edoxaban Impurity 7 (CAS 1072-98-6)
- Edoxaban Impurity 71 (CAS 1093351-29-1)
- Edoxaban Impurity N8 HCl (CAS 1190971-73-3)
- Edoxaban Impurity 47 (CAS 1210348-16-5)
- Edoxaban Impurity 74 (CAS 1210348-21-2)
- Edoxaban Impurity 20 (CAS 1210348-34-7)
- Edoxaban Tosylate Monohydrate (CAS 1229194-11-9)
Recommended Standards
- Atrasentan Impurity 52 (CAS 1059057-00-9)
- Brivaracetam Impurity 183 (CAS CATO-C4X-2007183)
- Piribedil Impurity 5 (CAS CATO-C4X-28137)
- trans-2-Nitro-cyclopropanecarboxylic acid ethyl ester (CAS 1287760-02-4)
- imidazo[1,2-a]pyrimidin-7-amine (CAS 462651-80-5)
- 2-Phenyl-2-[(propan-2-yl)amino]ethan-1-ol (CAS 68058-02-6)
- 1-(Bromomethyl)-2-(methoxymethyl)benzene (CAS 171055-42-8)
- 4-Bromo-2,2-difluoro-1,3-benzodioxole (CAS 144584-66-7)
- (1Z)-N-Hydroxy-4-pyrrolidin-1-ylbutanimidamide (CAS 885952-00-1)
- Peptide Impurity 05 (CAS 2322924-83-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com