Ibrutinib Impurity 151 CAS CATO-C4X-1064151
| CAS No. | CATO-C4X-1064151 |
| Molecular Formula | C14H10O5 |
| Molecular Weight | 258.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Ibrutinib Impurity 151 (C14H10O5) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 258.23 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Ibrutinib Impurity 151 (CAS CATO-C4X-1064151) is a certified pharmaceutical impurity reference standard with the molecular formula C14H10O5 and a molecular weight of 258.23 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ibrutinib Impurity 151 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10O5 |
| Molecular Weight | 258.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Ibrutinib Standards
- Ibrutinib Impurity 143 (CAS CATO-C4X-1064143)
- Ibrutinib Impurity 154 (CAS CATO-C4X-1064154)
- Ibrutinib Impurity 155 (CAS CATO-C4X-1064155)
- Ibrutinib Impurity 51 (CAS CATO-C4X-106451)
- Ibrutinib Impurity 181 (CAS 79888-54-3)
- Ibrutinib Impurity 103 (CAS CATO-C4X-1064103)
- Ibrutinib Impurity 104 (CAS CATO-C4X-1064104)
- Ibrutinib Impurity 117 (CAS CATO-C4X-1064117)
Recommended Standards
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