Ibrutinib Impurity 160 CAS CATO-C4X-1064160
| CAS No. | CATO-C4X-1064160 |
| Molecular Formula | C26H28N6O3 |
| Molecular Weight | 472.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ibrutinib Impurity 160 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Ibrutinib Impurity 160 (CAS CATO-C4X-1064160, C26H28N6O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ibrutinib Impurity 160 (C26H28N6O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C26H28N6O3 |
| Molecular Weight | 472.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Ibrutinib Standards
- Ibrutinib Impurity 137 (CAS CATO-C4X-1064137)
- Ibrutinib Impurity 169 (CAS CATO-C4X-1064169)
- Ibrutinib Impurity 44 (CAS 2031255-26-0)
- Ibrutinib M25, 98% (CAS 1839090-60-6)
- Ibrutinib Impurity 138 (CAS CATO-C4X-1064138)
- Ibrutinib Impurity 13 (Mixture of Diastereomers) (CAS 1654820-87-7)
- Ibrutinib Impurity 92 (CAS CATO-C4X-106492)
- Ibrutinib Impurity 93 (CAS CATO-C4X-106493)
Recommended Standards
- Argatroban Impurity 34 (CAS 74874-07-0)
- Argatroban Impurity 131 (CAS CATO-C4X-1007131)
- Azilsartan Impurity 186 (CAS CATO-C4X-1096186)
- Argatroban Impurity 130 (CAS CATO-C4X-1007130)
- Letermovir Impurity 67 (CAS CATO-C4X-291567)
- Toltrazuril Impurity 4 (CAS CATO-C4X-24024)
- Pyridoxine impurity 69 (CAS CATO-C4X-187769)
- ethyl 2-hydroxy-4,5,6,7-tetrahydro-1,3-benzothiazole-4-carboxylate (CAS 57001-10-2)
- 3-(3-Bromophenyl)-3-((tert-butoxycarbonyl)amino)propanoic acid (CAS 284493-58-9)
- (4'-Hydroxy-3'-methyl-[1,1'-biphenyl]-2-yl)(pyrrolidin-3-yl)methanone (CAS 1261996-45-5)
- (E)-3-((3,4-dichlorobenzyl)thio)-4-ethyl-5-styryl-4H-1,2,4-triazole (CAS 478065-61-1)
- (S)-6,7-Dihydro-5H-cyclopenta[b]pyridin-7-ol (CAS 887921-99-5)
- 4-(2-Bromophenyl)-2,6-dimethyl-3,5-pyridinedicarboxylic Acid-d10 Diethyl Ester (CAS 1329793-25-0)
- D-Asp15-Tirzepatide (CAS CATO-CPTD788919)
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