Ibrutinib Impurity 13 (Mixture of Diastereomers) CAS 1654820-87-7
| CAS No. | 1654820-87-7 |
| Molecular Formula | C25H26N6O4 |
| Molecular Weight | 474.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Ibrutinib Impurity 13 (Mixture of Diastereomers) (CAS 1654820-87-7, C25H26N6O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ibrutinib Impurity 13 (Mixture of Diastereomers) (C25H26N6O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 474.51 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ibrutinib Impurity 13 (Mixture of Diastereomers) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H26N6O4 |
| Molecular Weight | 474.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Nitrogen Atoms | 6 |
Related Ibrutinib Standards
- Ibrutinib Impurity 92 (CAS CATO-C4X-106492)
- Ibrutinib Impurity 93 (CAS CATO-C4X-106493)
- Ibrutinib Impurity 137 (CAS CATO-C4X-1064137)
- Ibrutinib Impurity 160 (CAS CATO-C4X-1064160)
- Ibrutinib Impurity 169 (CAS CATO-C4X-1064169)
- Ibrutinib Impurity 44 (CAS 2031255-26-0)
- Ibrutinib M25, 98% (CAS 1839090-60-6)
- Ibrutinib Impurity 3 (CAS 1288338-96-4)
Recommended Standards
- Z-Dbu(Fmoc) (R) (CAS 349547-09-7)
- Apixaban Impurity 6 (CAS 1074365-84-6)
- Boc-3-amino-5-(fmoc-amino)-benzoic acid (CAS 779335-06-7)
- Racecadotril Impurity 11 (CAS CATO-C4X-110611)
- Ozanimod Impurity 24 (CAS CATO-C4X-290224)
- Ertapenem Impurity C28 (CAS 147266-92-0)
- Lasmiditan Impurity 7 (CAS CATO-C4X-24787)
- 1-(4-Methoxyphenoxy)-3-(4-methylpiperazin-1-yl)propan-2-ol (CAS 300394-09-6)
- (5-(4-Fluorobenzyl)-2,4-dihydroxyphenyl)(isoindolin-2-yl)methanone (CAS 2134571-29-0)
- 4-(4-Methoxyphenyl)-1,3-dimethyl-1H-pyrazol-5-amine (CAS 1015846-18-0)
- 4-(Cyclopentyloxy)-3,5-difluoro-2-methylphenylboronic acid (CAS 2096336-27-3)
- 5-(4-((2,5-Dimethylphenyl)amino)phthalazin-1-yl)-2-methyl-N-((tetrahydrofuran-2-yl)methyl)benzenesulfonamide (CAS 442648-34-2)
- N-(2-(2-((2-Methoxyethyl)amino)-2-oxoethyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)thiophene-2-carboxamide (CAS 1105248-41-6)
- Semaglutide impurity 236 (CAS CATO-C4X-2226236)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com