Empagliflozin Impurity 151 CAS CATO-C4X-1065151

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1065151
Molecular FormulaC21H21IO5
Molecular Weight480.29 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Empagliflozin Impurity 151 CAS CATO-C4X-1065151 chemical structure

Description

Empagliflozin Impurity 151 (CAS CATO-C4X-1065151) is a certified pharmaceutical impurity reference standard with the molecular formula C21H21IO5 and a molecular weight of 480.29 g/mol.

The molecular framework of Empagliflozin Impurity 151 (C21H21IO5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Empagliflozin Impurity 151 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC21H21IO5
Molecular Weight480.29 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentI-containing

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