Empagliflozin Impurity 167 CAS CATO-C4X-1065167
| CAS No. | CATO-C4X-1065167 |
| Molecular Formula | C17H16BrClO2 |
| Molecular Weight | 367.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Empagliflozin Impurity 167 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Empagliflozin Impurity 167 (CAS CATO-C4X-1065167, C17H16BrClO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C17H16BrClO2, Empagliflozin Impurity 167 contains a steroid core, a hydroxyl group, an ether linkage, chlorine/bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 367.66 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H16BrClO2 |
| Molecular Weight | 367.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 105 (CAS 915095-90-8)
- Empagliflozin impurity 177 (CAS CATO-C4X-1065177)
- Empagliflozin impurity 178 (CAS CATO-C4X-1065178)
- Empagliflozin Impurity 25 (CAS 915095-89-5)
- Empagliflozin Impurity 66 (CAS 2744280-76-8)
- Empagliflozin impurity 274 (CAS 2744280-73-5)
- Empagliflozin Impurity 293 (CAS 1185339-44-9)
- Empagliflozin Impurity 102 (CAS CATO-C4X-1065102)
Recommended Standards
- 6,8-Dichloro-2-(chloromethyl)-3-(2,6-dimethylphenyl)quinazolin-4(3H)-one (CAS 338957-44-1)
- 4-(2-Methoxyphenyl)-5-methyl-2-(2,4,6-trichlorophenyl)-2H-imidazole (CAS 865658-13-5)
- N-Dodecyldodecanamide (CAS 33422-43-4)
- 6-Bromo-3-(3-chlorophenyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one (CAS 18009-11-5)
- Epinephrine /Adrenaline Impurity 121 (CAS CATO-C4X-1849121)
- Bumetanide Impurity 135 (CAS 30170-22-0)
- Lenacapavir Impurity 32 (CAS CATO-C4X-324832)
- 4-Cyano-N-(1,3-dioxoisoindolin-5-yl)benzamide (CAS 683235-33-8)
- 2-Chloro-4-ethynylbenzaldehyde (CAS 1849215-25-3)
- 1-(Difluoromethyl)-5-(methoxymethyl)-1H-pyrazole (CAS 1856041-63-8)
- (2S,4R)-4-Hydroxypyrrolidine-2-carboxamide Hydrochloride (CAS 32934-42-2)
- 5-Chloro-4-methyl-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-ol (CAS 2377609-35-1)
- 5-Cyclopropoxy-6-fluoro-N,N-dimethylpyridin-2-amine (CAS 1243317-72-7)
- Fibrinogen Related Peptide (CAS 80755-86-8)
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