Empagliflozin impurity 177 CAS CATO-C4X-1065177
| CAS No. | CATO-C4X-1065177 |
| Molecular Formula | C17H16BrClO2 |
| Molecular Weight | 367.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Empagliflozin impurity 177 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Empagliflozin impurity 177 (CAS CATO-C4X-1065177) is a certified pharmaceutical impurity reference standard with the molecular formula C17H16BrClO2 and a molecular weight of 367.66 g/mol.
Empagliflozin impurity 177 (C17H16BrClO2) contains a steroid core, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H16BrClO2 |
| Molecular Weight | 367.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 105 (CAS 915095-90-8)
- Empagliflozin Impurity 167 (CAS CATO-C4X-1065167)
- Empagliflozin impurity 178 (CAS CATO-C4X-1065178)
- Empagliflozin Impurity 25 (CAS 915095-89-5)
- Empagliflozin Impurity 66 (CAS 2744280-76-8)
- Empagliflozin impurity 274 (CAS 2744280-73-5)
- Empagliflozin Impurity 293 (CAS 1185339-44-9)
- Empagliflozin Impurity 102 (CAS CATO-C4X-1065102)
Recommended Standards
- 6,8-Dichloro-2-(chloromethyl)-3-(2,6-dimethylphenyl)quinazolin-4(3H)-one (CAS 338957-44-1)
- 4-(2-Methoxyphenyl)-5-methyl-2-(2,4,6-trichlorophenyl)-2H-imidazole (CAS 865658-13-5)
- N-(4-Chlorophenyl)-3,5-bis(trifluoromethyl)benzamide (CAS 106376-49-2)
- N-Dodecyldodecanamide (CAS 33422-43-4)
- Linagliptin Impurity 6 (CAS CATO-C4X-11016)
- Nicergoline Impurity 29 (CAS CATO-C4X-208529)
- N-Nitroso Diphenhydramine EP Impurity A (CAS 55855-43-1)
- N-(4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)cyclopropanecarboxamide (CAS 476278-60-1)
- 5-Bromo-8-chloroisoquinoline (CAS 956003-79-5)
- Tert-butyl (S)-6-(trifluoromethyl)-2,7-diazaspiro[3.5]Nonane-2-carboxylate (CAS 1956437-30-1)
- rel-tert-Butyl (3R,4S)-3-ethyl-4-hydroxypyrrolidine-1-carboxylate (CAS 1228880-43-0)
- Methyl 2-((2-methoxy-2-oxoethyl)thio)benzoate (CAS 6287-88-3)
- 2-(4,5-Dihydro-1H-imidazol-2-yl)pyrimidine (CAS 1254357-05-5)
- Des-Pro31-Tirzepatide (CAS CATO-CPTD788943)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com