Empagliflozin impurity 229 CAS CATO-C4X-1065229
| CAS No. | CATO-C4X-1065229 |
| Molecular Formula | C17H15ClO4 |
| Molecular Weight | 318.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Empagliflozin impurity 229 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Empagliflozin impurity 229 (CAS CATO-C4X-1065229), a pharmacopoeial impurity reference standard (molecular formula C17H15ClO4, MW 318.75 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution, Empagliflozin impurity 229 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 318.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Empagliflozin impurity 229 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15ClO4 |
| Molecular Weight | 318.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 147 (CAS 501009-13-8)
- Empagliflozin Impurity 135 (CAS 2760767-62-0)
- Empagliflozin Impurity 162 (CAS 1715629-30-3)
- Empagliflozin Impurity 172 (CAS CATO-C4X-1065172)
- Empagliflozin impurity 225 (CAS CATO-C4X-1065225)
- Empagliflozin Impurity 282 (CAS 1712958-06-9)
- Empagliflozin Impurity 151 (CAS 915095-85-1)
- Empagliflozin Impurity 63 (CAS 1360568-68-8)
Recommended Standards
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- Cipepofol Impurity 3 (CAS 1637741-59-3)
- Metoclopramide Impurity 26 (CAS CATO-C4X-141526)
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- 3-(Benzo[d][1,3]dioxol-5-yl)-2-cyanoacrylic Acid (CAS 51066-70-7)
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