Empagliflozin Impurity 307 CAS CATO-C4X-1065307
| CAS No. | CATO-C4X-1065307 |
| Molecular Formula | C21H23IO4 |
| Molecular Weight | 466.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Empagliflozin Impurity 307 (CAS CATO-C4X-1065307, C21H23IO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, iodine substitution, Empagliflozin Impurity 307 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 466.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Empagliflozin Impurity 307 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H23IO4 |
| Molecular Weight | 466.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | I-containing |
Related Empagliflozin Standards
- Empagliflozin impurity 243 (CAS CATO-C4X-1065243)
- Empagliflozin Impurity 170 (CAS 1620758-30-6)
- Empagliflozin impurity 181 (CAS 2452301-36-7)
- Empagliflozin impurity 188 (CAS CATO-C4X-1065188)
- Empagliflozin impurity 189 (CAS CATO-C4X-1065189)
- Empagliflozin impurity 206 (CAS CATO-C4X-1065206)
- Empagliflozin impurity 210 (CAS CATO-C4X-1065210)
- Empagliflozin Impurity 218 (CAS CATO-C4X-1065218)
Recommended Standards
- Bosutinib Impurity 14 (CAS CATO-C4X-184714)
- N-(4-(((4-bromophenyl)thio)methyl)phenyl)-3-(trifluoromethyl)benzamide (CAS 321431-75-8)
- Amisulbrom (CAS 348635-87-0)
- 4-Nitrobenzoyl-6-selenoinosine (CAS 40144-12-5)
- Rosuvastatin EP Impurity K Calcium Salt (Z-isomer) (CAS CATO-C4X-1169178)
- Estradiol Valerate EP Impurity I (CAS CATO-C4X-28427)
- Cefepime Impurity 27 (CAS CATO-C4X-119327)
- Finerenone Impurity 21 (CAS 1017082-75-5)
- (2-(1-Methyl-1h-pyrazol-4-yl)tetrahydro-2h-pyran-3-yl)methanamine (CAS 1479935-12-0)
- 2-Ethoxy-4-(3-(3-methoxyphenyl)-1H-1,2,4-triazol-5-yl)phenol (CAS 1416347-13-1)
- Boc-l-ile-nh2 (CAS 94888-34-3)
- 3-(1H-Benzimidazol-1-yl)-N-hydroxypropanimidamide (CAS 4404-30-2)
- 2-((3-Chlorophenyl)amino)-1H-purin-6(9H)-one (CAS 123994-67-2)
- Tumor Targeted Pro-Apoptotic Peptide (CAS 1926163-30-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com