Empagliflozin impurity 206 CAS CATO-C4X-1065206
| CAS No. | CATO-C4X-1065206 |
| Molecular Formula | C23H27ClO8 |
| Molecular Weight | 466.91 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Empagliflozin impurity 206 (CAS CATO-C4X-1065206, C23H27ClO8) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C23H27ClO8, Empagliflozin impurity 206 contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 466.91 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Empagliflozin impurity 206 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H27ClO8 |
| Molecular Weight | 466.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 170 (CAS 1620758-30-6)
- Empagliflozin impurity 181 (CAS 2452301-36-7)
- Empagliflozin impurity 188 (CAS CATO-C4X-1065188)
- Empagliflozin impurity 189 (CAS CATO-C4X-1065189)
- Empagliflozin impurity 210 (CAS CATO-C4X-1065210)
- Empagliflozin Impurity 218 (CAS CATO-C4X-1065218)
- Empagliflozin impurity 224 (CAS CATO-C4X-1065224)
- Empagliflozin Impurity 49 (CAS 1279691-35-8)
Recommended Standards
- Ethyl 5-[({1-[(1Z)-{[(4-chlorophenyl)methoxy]imino}methyl]naphthalen-2-yl}oxy)methyl]-4,5-dihydro-1,2-oxazole-3-carboxylate (CAS 321432-26-2)
- Empagliflozin Impurity 77 (CAS 2137418-13-2)
- (2E)-3-Amino-3-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-cyano-N-phenylprop-2-enethioamide (CAS 338959-69-6)
- Empagliflozin Impurity 87 (CAS CATO-C4X-106587)
- Spiramycin EP impurity F (CAS CATO-C4X-232510)
- Iopamidol EP Impurity D (CAS 87932-11-4)
- Olaparib Impurity 67 (CAS 227609-85-0)
- 1,3-Benzenedicarboxylic acid, polymer with 1,2-ethanediol and 1,3,5-tris(2-hydroxyethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione (CAS 67906-79-0)
- lithium(1+) ion 2-[2-(3-ethylpyrrolidin-1-yl)-1,3-thiazol-4-yl]acetate (CAS 2059941-81-8)
- Dexmedetomidine-d3 L-Tartrate (CAS CATO-C4X-123037)
- Clemastine Impurity 14 (CAS CATO-C4X-183714)
- (3-Chloroprop-1-yn-1-yl)cyclohexane (CAS 55723-99-4)
- 3-Chloro-5-(naphthalen-2-ylsulfonyl)-1,2,4-thiadiazole (CAS 1000575-39-2)
- Insulin Degludec Impurity 5 (CAS CATO-C4X-21575)
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