Imatinib EP Impurity D CAS CATO-C4X-106815
| CAS No. | CATO-C4X-106815 |
| Molecular Formula | C53H51N12O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 923.52 g/mol gives Imatinib EP Impurity D distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Imatinib EP Impurity D (CAS CATO-C4X-106815), a pharmacopoeial impurity reference standard (molecular formula C53H51N12O2Cl, MW 923.52 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Imatinib EP Impurity D (C53H51N12O2Cl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 34.0, corresponding to approximately 34 ring(s) or double-bond equivalent(s). With a molecular weight of 923.52 g/mol, it falls into the high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Imatinib EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C53H51N12O2 Cl |
| Molecular Weight | 923.52 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 34.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 12 |
Related Imatinib Standards
- Imatinib Impurity 10 (CAS 1026753-54-7)
- 6-Methyl Imatinib (CAS 1032314-85-4)
- Imatinib Impurity 17 (CAS 106261-49-8)
- Imatinib Impurity 48 (CAS 106261-64-7)
- Imatinib-d8 (CAS 1092942-82-9)
- Imatinib Impurity 18 (CAS 112696-91-0)
- Imatinib Impurity 48 (CAS 1131605-15-6)
- Imatinib-d3 (N-methyl-d3) (CAS 1134803-18-1)
Recommended Standards
- Trazodone Impurity 66 (CAS CATO-C4X-177266)
- Barloxavir impurity C718 (CAS 1370250-38-6)
- Mexiletine Impurity 11 (CAS 284486-96-0)
- 3-amino-10H-acridine-9-thione (CAS 129821-08-5)
- (1S,2S)-2-(Aminomethyl)cycloheptan-1-ol hydrochloride (CAS 42418-76-8)
- 2-(Trifluoromethyl)thiophen-3-amine (CAS 1822907-35-6)
- Methyl (2S)-3-carbamoyl-2-(1,3-dioxoisoindol-2-yl)propanoate (CAS 1820574-75-1)
- (R)-2-Amino-3-(3-bromo-4-hydroxyphenyl)propanoic acid (CAS 1241680-33-0)
- 2-Bromo-1,3-bis(2-methoxyphenyl)propane-1,3-dione (CAS 937602-32-9)
- Liraglutide Impurity 26 (CAS CATO-C4X-199226)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com