Tenofovir disoproxil Impurity 133 CAS CATO-C4X-1076133

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1076133
Molecular FormulaC34H51N11O18P2
Molecular Weight963.78 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Tenofovir disoproxil Impurity 133 CAS CATO-C4X-1076133 chemical structure

Description

CATO supplies Tenofovir disoproxil Impurity 133 (CAS CATO-C4X-1076133), a pharmacopoeial impurity reference standard (molecular formula C34H51N11O18P2, MW 963.78 g/mol) used for the identification and quantification of trace impurities in APIs.

Tenofovir disoproxil Impurity 133 (C34H51N11O18P2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Tenofovir disoproxil Impurity 133 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC34H51N11O18P2
Molecular Weight963.78 g/mol
Purity≥95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms11

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