Tenofovir Alafenamide Impurity 35 CAS CATO-C4X-179735
| CAS No. | CATO-C4X-179735 |
| Molecular Formula | C42H56N12O10P2S |
| Molecular Weight | 982.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tenofovir Alafenamide Impurity 35.
As a process- or degradation-related impurity, Tenofovir Alafenamide Impurity 35 (CAS CATO-C4X-179735, C42H56N12O10P2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Tenofovir Alafenamide Impurity 35 (C42H56N12O10P2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a phosphate ester group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 21.0, corresponding to approximately 21 ring(s) or double-bond equivalent(s). With a molecular weight of 982.98 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tenofovir Alafenamide Impurity 35 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C42H56N12O10P2S |
| Molecular Weight | 982.98 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 21.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 12 |
| Sulfur Atoms | 1 |
Related Tenofovir Standards
- Tenofovir disoproxil Impurity 130 (CAS CATO-C4X-1076130)
- Tenofovir disoproxil Impurity 133 (CAS CATO-C4X-1076133)
- Tenofovir disoproxil Impurity 134 (CAS CATO-C4X-1076134)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir disoproxil Impurity 116 (CAS 2241284-68-2)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 119 (CAS CATO-C4X-1076119)
- Tenofovir disoproxil Impurity 132 (CAS CATO-C4X-1076132)
Recommended Standards
- N,N'-(((6-((9,10-Dioxo-9,10-dihydroanthracen-1-yl)amino)-1,3,5-triazine-2,4-diyl)bis(azanediyl))bis(9,10-dioxo-9,10-dihydroanthracene-5,1-diyl))dibenzamide (CAS 83742-16-9)
- Urechistachykinin II (CAS 149097-04-1)
- (OC-6-13)-[1,1'-(1S)-[1,1'-Binaphthalene]-2,2'-diylbis[1,1-diphenylphosphine-κP]]dichloro[2,5-di(amino-κN)-1,2,5,6-tetradeoxy-3,4-O-(1-methylethylidene)-D-mannitol]ruthenium (CAS 466696-02-6)
- Mupirocin Dimer 1 (CAS CATO-C4X-170619)
- Oseltamivir Impurity 75 (CAS CATO-C4X-172075)
- Febuxostat Impurity 13 (CAS 160844-75-7)
- Aripiprazole Impurity 29 Bromide (CAS CATO-C4X-100829)
- 1-Butyl-5-(furan-2-yl)-5,8-dihydropyrimido[4,5-d]pyrimidine-2,4,7(1H,3H,6H)-trione (CAS 1170406-22-0)
- 12H-Dibenzo[d,g][1,3,2]dioxaphosphocin, 2,4,8,10-tetrakis(1,1-dimethylethyl)-6-hydroxy-, 6-oxide, lithium salt (1:1) (CAS 85209-93-4)
- 1-(4-(Aminomethyl)phenyl)-2-(4-fluorophenyl)ethan-1-one (CAS 1017781-71-3)
- 2-(Aminomethyl)-3-(difluoromethyl)-5-(trifluoromethyl)pyridine-6-acetonitrile (CAS 1361732-49-1)
- 2-(Benzyloxy)-4,5-dimethoxybenzaldehyde (CAS 14382-86-6)
- 3-Bromo-2-methoxy-6-methyl-5-nitropyridine (CAS 1351813-58-5)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
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