Tenofovir disoproxil Impurity 9 CAS CATO-C4X-10769
| CAS No. | CATO-C4X-10769 |
| Molecular Formula | C19H31N6O9P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tenofovir disoproxil Impurity 9 (CAS CATO-C4X-10769), a pharmacopoeial impurity reference standard (molecular formula C19H31N6O9PC4H4O4, MW 634.54 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Tenofovir disoproxil Impurity 9 (C19H31N6O9PC4H4O4) contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.5, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 634.54 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H31N6O9P C4H4O4 |
| Molecular Weight | 634.54 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir disoproxil Impurity 28 (CAS 1115-59-9)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
Recommended Standards
- Amoxicillin Dimer Impurity (CAS 210289-72-8)
- Atrasentan Impurity 105 (CAS 1059052-12-8)
- Furosemide Impurity 40 (CAS 2309465-74-3)
- 2-(3-Fluorophenyl)pyrimidine-4-carboxylic acid (CAS 1315364-03-4)
- 2-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,7-naphthyridine (CAS 794461-85-1)
- 2-(5-Bromo-1H-indol-3-yl)propan-1-ol (CAS 1935477-85-2)
- Ethyl ((diethoxyphosphoryl)methylene)carbamate (CAS 62779-40-2)
- 4-Hydroxy-7-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)naphthalene-2-sulfonic acid (CAS 85136-68-1)
- 1-Chloro-5-isopropoxypentane (CAS 1097787-42-2)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com