Buspirone Impurity 03 CAS 42940-56-7
| CAS No. | 42940-56-7 |
| Molecular Formula | C11H11N3O2 |
| Molecular Weight | 217.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Buspirone Impurity 03 (CAS 42940-56-7, C11H11N3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C11H11N3O2, Buspirone Impurity 03 contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 217.22 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Buspirone Impurity 03 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11N3O2 |
| Molecular Weight | 217.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Nitrogen Atoms | 3 |
Related Buspirone Standards
- Buspirone Impurity 9 (CAS 13220-24-1)
- Buspirone Impurity 22 (CAS 223461-35-6)
- Buspirone Impurity 42 (CAS CATO-C4X-125842)
- Buspirone EP Impurity G (CAS 84746-24-7)
- Buspirone Impurity 14 (CAS 60143-00-2)
- Buspirone Impurity 20 (CAS 1821194-01-7)
- Buspirone EP Impurity L (CAS 21098-11-3)
- Buspirone EP Impurity A-d8 (Buspirone USP Related Compound A-d8) (CAS 1309283-31-5)
Recommended Standards
- Bis(4-acetamidophenyl) carbonate (CAS 19959-81-0)
- Carbaryl Impurity 10 (CAS 32263-74-4)
- Benzyl furan-3-ylcarbamate (CAS 499202-76-5)
- Carbaryl Impurity 11 (CAS 32263-67-5)
- Olaparib Impurity 14 (CAS 420846-72-6)
- Vibegron Impurity 16 (CAS CATO-C4X-237616)
- Lenvatinib Impurity 181 (CAS CATO-C4X-1140181)
- Ir[FCF3(CF3)ppy]2(dtbbpy)PF6 (CAS 2222402-20-0)
- 6-Methoxy-4-methylbenzo[d]thiazole (CAS 1190310-57-6)
- 2-(3-Chloro-2-methyl-5-nitrophenyl)acetic acid (CAS 1804889-71-1)
- 2-(3,5-Diphenyl-1H-1,2,4-triazol-1-yl)acetic acid (CAS 1170981-94-8)
- (R)-tert-Butyl (5,6,7,8-tetrahydroquinoxalin-5-yl)carbamate (CAS 911826-35-2)
- Emamectin (CAS 119791-41-2)
- Des-Pro-Pro-Tirzepatide (CAS CATO-CPTD788696)
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