Ambroxol Impurity 87 CAS CATO-C4X-108587
| CAS No. | CATO-C4X-108587 |
| Molecular Formula | C16H22Br2N2O3 |
| Molecular Weight | 450.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ambroxol Impurity 87 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ambroxol Impurity 87 (CAS CATO-C4X-108587) is a certified pharmaceutical impurity reference standard with the molecular formula C16H22Br2N2O3 and a molecular weight of 450.17 g/mol.
The molecular framework of Ambroxol Impurity 87 (C16H22Br2N2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ambroxol Impurity 87 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H22Br2N2O3 |
| Molecular Weight | 450.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Ambroxol Standards
- Ambroxol impurity 108 (CAS 73220-00-5)
- Ambroxol Impurity 91 (CAS CATO-C4X-108591)
- Ambroxol Impurity 90 (CAS CATO-C4X-108590)
- Ambroxol Impurity 101 (CAS CATO-C4X-1085101)
- Ambroxol impurity 115 (CAS CATO-C4X-1085115)
- Ambroxol Impurity 13 (CAS 305867-38-3)
- Ambroxol impurity 05 (CAS CATO-C4X-1085105)
- Ambroxol Impurity 93 (CAS CATO-C4X-108593)
Recommended Standards
- Bromhexine impurity 53 (CAS CATO-C4X-106053)
- 3-(2,6-Dichlorophenyl)-5-{1-[4-(trifluoromethyl)phenyl]-1H-1,2,3-triazol-4-yl}-1,2-oxazole-4-carbonitrile (CAS 900019-76-3)
- 3,5-Dibromo-2,6-dimethoxy-N-(2-(piperidin-1-yl)ethyl)benzamide (CAS 89653-92-9)
- (1R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro[1,1'-binaphthalene]-2,2'-diamine (CAS 950769-11-6)
- Lansoprazole impurity 72 (CAS 2138848-89-0)
- Flunarizine EP Impurity C HCl (CAS 90830-31-2(free base))
- Esomeprazole H215 Impurity Sodium Salt (CAS 1803449-15-1)
- Diethyl 2-(5-ethoxycarbonyl-3-nitro-2-pyridyl)propanedioate (CAS 1630906-48-7)
- 4-Chloro-3-fluoro-2-morpholinomethyl benzophenone (CAS 898750-65-7)
- N-(3-Fluorophenyl)-2-((6-methyl-4-oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 905687-11-8)
- 5,7-Dichloro-6-ethyl-1,3-benzoxazol-2-amine (CAS 1820706-11-3)
- Methyl 2-(4-Vinylphenyl)acetate (CAS 62667-42-9)
- 2-(N-ethylacetamido)ethane-1-sulfonic acid (CAS 1803609-74-6)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com