Ambroxol Impurity 117 CAS CATO-C4X-1085117
| CAS No. | CATO-C4X-1085117 |
| Molecular Formula | 2*C19H28Br2N2O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ambroxol Impurity 117 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Ambroxol Impurity 117 (CAS CATO-C4X-1085117, C19H28Br2N2O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ambroxol Impurity 117 (C19H28Br2N2O6) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ambroxol Impurity 117 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | 2*C19H28Br2N2O6 |
| Molecular Weight | 540.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Ambroxol Standards
- Ambroxol Impurity 28 (Ambroxol Monobromo) (CAS 101900-43-0)
- Ambroxol Impurity 33 HCl (CAS 101900-44-1)
- Ambroxol impurity 61 (CAS 104670-74-8)
- Ambroxol impurity 68 (CAS 105735-86-2)
- Ambroxol EP Impurity D (CAS 107814-37-9)
- Ambroxol D5DISCONTINUED, offer A575902 (CAS 1246818-80-3)
- Ambroxol impurity 113 (CAS 131417-90-8)
- Ambroxol impurity 116 (CAS 1373889-89-4)
Recommended Standards
- Formoterol Impurity N1 (CAS 43229-66-9)
- Metoclopramide EP Impurity A HCl (CAS 5608-13-9(Free Base))
- Cefixime Impurity 75 (CAS CATO-C4X-113975)
- 2-Chloro-3-iodocyclohepta[b]pyrrole (CAS 503865-68-7)
- 3-Fluoro-4,4'-dichlorobiphenyl (CAS 1236120-19-6)
- Methyl 2-(3-fluoro-4-methoxyphenyl)acetate (CAS 588-14-7)
- 4-(Ethylsulfonyl)-3-(m-tolyl)-1H-pyrazole (CAS 1707391-65-8)
- Potassium trifluoro(p-tolylethynyl)borate (CAS 664374-21-4)
- 3-(6-Benzoyl-2-oxobenzo[d]oxazol-3(2H)-yl)propanoic acid (CAS 76752-01-7)
- Polymyxin B nonapeptide (CAS 86408-36-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com