Tadalafil Impurity 161 CAS CATO-C4X-1087161
| CAS No. | CATO-C4X-1087161 |
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tadalafil Impurity 161 (CAS CATO-C4X-1087161), a pharmacopoeial impurity reference standard (molecular formula C12H13NO3, MW 219.24 g/mol) used for the identification and quantification of trace impurities in APIs.
Tadalafil Impurity 161 (C12H13NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tadalafil Impurity 161 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Tadalafil Standards
- Tadalafil Impurity 36 (CAS 4299-70-1)
- Tadalafil Impurity 49 (CAS 1379883-12-1)
- Tadalafil Impurity 88 (CAS 22032-65-1)
- Tadalafil Impurity 117 (CAS CATO-C4X-1087117)
- Tadalafil Impurity 119 (CAS CATO-C4X-1087119)
- Tadalafil Impurity N27 (CAS 21753-16-2)
- Tadalafil Impurity 163 (CAS CATO-C4X-1087163)
- Tadalafil Impurity 164 (CAS 58979-02-5)
Recommended Standards
- cis-Zeatin (CAS 32771-64-5)
- Dronedarone Impurity 45 (CAS 133238-87-6)
- 915923-70-5 (5,7-Dimethyl-2-oxo-2,3-dihydro-1H-indol-3-yl)acetic acid DTXSID60661656 (CAS 915923-70-5)
- Gefitinib Impurity 91 (CAS CATO-C4X-111791)
- Minodronic Impurity 26 (CAS CATO-C4X-124126)
- Posaconazole Impurity 62 (CAS CATO-C4X-120862)
- Azelastine Impurity 48 (CAS CATO-C4X-139648)
- 4-(4-Methoxyphenoxy)-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 860610-38-4)
- H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Ser-OH (M-2500.0001) (CAS 91999-74-5)
- Methyl (2Z)-2-(4-ethoxybenzenesulfonyl)-3-[(4-ethylphenyl)amino]prop-2-enoate (CAS 1327179-33-8)
- 8-Chloro-5-fluorochroman-4-amine (CAS 1337158-52-7)
- 9-Phenylnonan-1-ol (CAS 3208-26-2)
- Butylphthalide (CAS 6066-49-5)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com