Gefitinib Impurity 91 CAS CATO-C4X-111791
| CAS No. | CATO-C4X-111791 |
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Gefitinib Impurity 91 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Gefitinib Impurity 91 (CAS CATO-C4X-111791, C12H13NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Gefitinib Impurity 91 (C12H13NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Gefitinib Standards
- Gefitinib Impurity 80 (CAS CATO-C4X-111780)
- Gefitinib Impurity 88 (CAS CATO-C4X-111788)
- Gefitinib Impurity 73 (CAS CATO-C4X-111773)
- Gefitinib Impurity 78 (CAS CATO-C4X-111778)
- Gefitinib Impurity 92 (CAS CATO-C4X-111792)
- Gefitinib Impurity 79 (CAS CATO-C4X-111779)
- Gefitinib Impurity 25 (CAS 385784-68-9)
- Gefitinib Impurity 40 (CAS 179688-53-0)
Recommended Standards
- Dronedarone Impurity 45 (CAS 133238-87-6)
- Febuxostat Impurity 38 (CAS 528607-60-5)
- Tadalafil Impurity 161 (CAS CATO-C4X-1087161)
- Cefradine Impurity 17 (CAS CATO-C4X-121517)
- Gefitinib Impurity 97 (CAS CATO-C4X-111797)
- Lobeline EP Impurity C (CAS CATO-C4X-181821)
- Galanthamine Impurity 27 (CAS CATO-C4X-143527)
- Methyl 3-[4-(chlorosulfonyl)phenoxy]propanoate (CAS 56077-79-3)
- 5,5-Difluoropiperidine-2-carboxylic Acid (CAS 1255663-89-8)
- 1,3-Dibromo-2,5-dimethylbenzene (CAS 66788-13-4)
- 5-Chloro-2,3-dimethoxy-4-nitropyridine (CAS 1881321-61-4)
- (E)-3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)-N-(pyridin-3-ylmethyl)acrylamide (CAS 956691-12-6)
- 2-Amino-4-chloro-6-(trifluoromethyl)pyrimidine-5-carbonitrile (CAS 951753-89-2)
- Semaglutide238 (CAS CATO-C4X-2226238)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com