Apixaban Impurity 129 CAS CATO-C4X-1088129
| CAS No. | CATO-C4X-1088129 |
| Molecular Formula | C15H17N3O3 |
| Molecular Weight | 287.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Apixaban Impurity 129 (C15H17N3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Apixaban Impurity 129 (CAS CATO-C4X-1088129) is a certified pharmaceutical impurity reference standard with the molecular formula C15H17N3O3 and a molecular weight of 287.31 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Apixaban Impurity 129 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H17N3O3 |
| Molecular Weight | 287.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related Apixaban Standards
- Apixaban Impurity 148 (CAS CATO-C4X-1088148)
- Apixaban Impurity 114 (CAS CATO-C4X-1088114)
- Apixaban Impurity 116 (CAS CATO-C4X-1088116)
- Apixaban Impurity 131 (CAS CATO-C4X-1088131)
- Apixaban Impurity 84 (CAS 881386-01-2)
- Apixaban Impurity 130 (CAS CATO-C4X-1088130)
- Apixaban Impurity 117 (CAS CATO-C4X-1088117)
- Apixaban Impurity 115 (CAS CATO-C4X-1088115)
Recommended Standards
- 1-(2-(2-aminoethyl)-4,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethan-1-one (CAS CATO-C3D-262303)
- Palbociclib Impurity 202 (CAS CATO-C4X-1125202)
- 3-(2-Methoxy-phenylcarbamoyl)-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid 3-(2-methoxy-phenylcarbamoyl)-bicyclo[ 61894-11-9 (CAS 61894-11-9)
- Itopride Impurity 1 (CAS 943518-63-6)
- Indacaterol Impurity 5 (CAS 62978-73-8)
- Procaine Impurity 6 (CAS CATO-C4X-26236)
- Flumazenil Impurity 17 (CAS CATO-C4X-143217)
- 8-Methylquinoxalin-2-ol (CAS 61148-22-9)
- 1-Cyclopentyl-N-(4-fluorobenzyl)-1H-pyrazol-4-amine hydrochloride (CAS 1856077-82-1)
- 5-((1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino)-5-oxopentanoic acid (CAS 37833-20-8)
- 1-(3-Amino-3-oxopropyl)piperidine-3-carboxylic acid (CAS 876717-47-4)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(4-((tert-butoxycarbonyl)amino)phenyl)acetic acid (CAS 265321-13-9)
- 2-(5-((3,4-Dichlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)pyridine (CAS 618414-77-0)
- Semaglutide impurity 236 (CAS CATO-C4X-2226236)
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