Apixaban Impurity 117 CAS CATO-C4X-1088117
| CAS No. | CATO-C4X-1088117 |
| Molecular Formula | C12H13ClN2O4 |
| Molecular Weight | 284.70 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Apixaban Impurity 117 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Apixaban Impurity 117 (CAS CATO-C4X-1088117, C12H13ClN2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C12H13ClN2O4, Apixaban Impurity 117 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 284.70 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C12H13ClN2O4 |
| Molecular Weight | 284.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Apixaban Standards
- Apixaban Impurity 114 (CAS CATO-C4X-1088114)
- Apixaban Impurity 116 (CAS CATO-C4X-1088116)
- Apixaban Impurity 131 (CAS CATO-C4X-1088131)
- Apixaban Impurity 148 (CAS CATO-C4X-1088148)
- Apixaban Impurity 129 (CAS CATO-C4X-1088129)
- Apixaban Impurity 84 (CAS 881386-01-2)
- Apixaban Impurity 130 (CAS CATO-C4X-1088130)
- Apixaban Impurity 115 (CAS CATO-C4X-1088115)
Recommended Standards
- Erlotinib impurity 129 (CAS CATO-C4X-1069129)
- Avatrombopag Impurity 18 (CAS 958457-83-5)
- 667436-24-0 7761AE 8-Chloro-2-pyridin-3-ylquinoline-4-carboxylic acid C15H9ClN2O2 (CAS 667436-24-0)
- tert-Butyl 2-(chloromethyl)-5-fluoro-1H-benzo[d]imidazole-1-carboxylate (CAS 1002750-44-8)
- Furosemide Impurity 57 (CAS 19377-82-3)
- Posaconazole impurity 238 (CAS CATO-C4X-1208238)
- Bicalutamide Impurity 31 (CAS CATO-C4X-101331)
- 5-Hydroxy-1-methyl-1H-benzo[d]imidazol-2(3H)-one (CAS 89945-35-7)
- 1-Ethyl-6-sulfanyl-1H-pyrazolo[3,4-d]pyrimidin-4-ol (CAS 832746-55-1)
- (2-Hydroxy-6-(piperidin-2-yl)pyridin-4-yl)boronic acid (CAS 2256708-73-1)
- 3-(4-Chloro-2-fluorophenoxy)pyrrolidine (CAS 946727-20-4)
- (R)-3-(1-Methyl-1H-indol-3-yl)butanenitrile (CAS 429689-23-6)
- Atorvastatin Impurity N4 (CAS 62148-67-8)
- Neuropeptide Y (free acid) (human, rat) trifluoroacetate salt (CAS 99575-89-0)
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