Alectinib Impurity 73 CAS CATO-C4X-283673
| CAS No. | CATO-C4X-283673 |
| Molecular Formula | C34H46N4O4 |
| Molecular Weight | 574.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Alectinib Impurity 73 (CAS CATO-C4X-283673, C34H46N4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Alectinib Impurity 73 (C34H46N4O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Alectinib Impurity 73 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C34H46N4O4 |
| Molecular Weight | 574.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Alectinib Standards
- Alectinib Impurity 50 (CAS CATO-C4X-283650)
- Alectinib Impurity 88 (CAS CATO-C4X-283688)
- Alectinib Impurity 47 (CAS CATO-C4X-283647)
- Alectinib Impurity 64 (CAS CATO-C4X-283664)
- Alectinib Impurity 82 (CAS CATO-C4X-283682)
- Alectinib Impurity 44 (CAS CATO-C4X-283644)
- Alectinib Impurity 83 (CAS CATO-C4X-283683)
- Alectinib Impurity 74 (CAS CATO-C4X-283674)
Recommended Standards
- LLY-507, 98%, a potent and selective inhibitor of protein-lysine methyltransferase SMYD2 (CAS 1793053-37-8)
- Abemaciclib impurity 121 (CAS CATO-C4X-2937121)
- Dexamethasone dodecyl ester (CAS CATO-C4X-116572)
- Benzylpenicillin (Benzathine) Tetrahydrate EP Impurity C (CAS CATO-C4X-189943)
- Atrasentan Impurity 78 (CAS 1058551-22-6)
- Elacestrant impurity 9 (CAS 3026845-27-9)
- Ramelteon Impurity 15 (CAS 880152-61-4)
- 4-((Allyloxy)methyl)benzaldehyde (CAS 216384-74-6)
- 2-aminohex-5-enoic acid hydrochloride (CAS 1237001-51-2)
- Amiodarone Hydrochloride EP Impurity F (CAS 147030-50-0)
- 2-Methoxyphenyl carbonochloridate (CAS 2293-75-6)
- 1,3-Dichloro-2-propanol-d5 (CAS 1173020-20-6)
- 2-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]-N-(2-methylphenyl)acetamide (CAS 1775444-53-5)
- D-Tyr1-Tirzepatide (CAS CATO-CPTD788928)
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