Apixaban Impurity 183 CAS CATO-C4X-1088183
| CAS No. | CATO-C4X-1088183 |
| Molecular Formula | C20H17N5O5 |
| Molecular Weight | 407.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 407.38 g/mol gives Apixaban Impurity 183 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Apixaban Impurity 183 (CAS CATO-C4X-1088183), a pharmacopoeial impurity reference standard (molecular formula C20H17N5O5, MW 407.38 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Apixaban Impurity 183 (C20H17N5O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Apixaban Impurity 183 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H17N5O5 |
| Molecular Weight | 407.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Apixaban Standards
- Apixaban Impurity 177 (CAS CATO-C4X-1088177)
- Apixaban Impurity 185 (CAS CATO-C4X-1088185)
- Apixaban Impurity 11 (CAS 503615-07-4)
- Apixaban Impurity 161 (CAS CATO-C4X-1088161)
- Apixaban Impurity 180 (CAS CATO-C4X-1088180)
- Apixaban Impurity 59 (CAS CATO-C4X-108859)
- Apixaban Impurity 140 (CAS CATO-C4X-1088140)
- Apixaban Impurity 73 (CAS CATO-C4X-108873)
Recommended Standards
- (2S)-2-(((9H-fluoren-9-yl)methoxy)carbonyl)-5,5,5-trifluoro-4-methylpentanoic acid 777946-04-0 A13354 Fmoc-D,L-5,5,5-trifluoroleucine (CAS 777946-04-0)
- Ethyl 2-(3-cyclopropyl-6-(1-ethyl-1H-pyrazol-4-yl)-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 1171944-79-8)
- Trimethyl 2,2':6',2''-Terpyridine-4,4',4''-tricarboxylate (CAS 330680-46-1)
- (1S,2R)-4-(3-Cyano-5-fluorophenoxy)-2-fluoro-7-(methylsulfonyl)-2,3-dihydro-1H-inden-1-yl acetate (CAS 1672668-25-5)
- Bempedoic Acid Impurity 19 (CAS CATO-C4X-218919)
- N-Nitroso Dalilesen impurity 37 (CAS CATO-C4X-301037)
- Nitroso Perindopril EP impurity O (CAS CATO-C4X-125252)
- 2,2,5-Trimethyl-3-(1-phenylethoxy)-4-phenyl-3-azahexane 227000-59-1 Alkoxyamine NMP initiator N-tert-Butyl-N-(2-methyl-1-phenylpropyl)-O-(1-phenylethyl)hydroxylamine (CAS 227000-59-1)
- Naphtho[2,1-b]benzofuran-8-ylboronic acid (CAS 1446516-26-2)
- Roxadustat Impurity 86 (CAS CATO-C4X-221386)
- (2R,4R)-4-Hydroxy-N,1-dimethylpyrrolidine-2-carboxamide (CAS 849345-16-0)
- tert-Butyl 3-(2-aminocyclobutyl)pyrrolidine-1-carboxylate (CAS 1823264-88-5)
- N-(2-(Furan-2-yl)phenyl)-3-(trifluoromethyl)benzenesulfonamide (CAS 663595-93-5)
- Semaglutide impurity 250 (CAS CATO-C4X-2226250)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com