Apixaban Impurity 140 CAS CATO-C4X-1088140
| CAS No. | CATO-C4X-1088140 |
| Molecular Formula | C20H26N4O5 |
| Molecular Weight | 402.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 402.44 g/mol gives Apixaban Impurity 140 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Apixaban Impurity 140 (CAS CATO-C4X-1088140), a pharmacopoeial impurity reference standard (molecular formula C20H26N4O5, MW 402.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Apixaban Impurity 140 (C20H26N4O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 402.44 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Apixaban Impurity 140 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H26N4O5 |
| Molecular Weight | 402.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Apixaban Standards
- Apixaban Impurity 180 (CAS CATO-C4X-1088180)
- Apixaban Impurity 161 (CAS CATO-C4X-1088161)
- Apixaban Impurity 11 (CAS 503615-07-4)
- Apixaban Impurity 177 (CAS CATO-C4X-1088177)
- Apixaban Impurity 183 (CAS CATO-C4X-1088183)
- Apixaban Impurity 185 (CAS CATO-C4X-1088185)
- Apixaban impurity 158 (CAS 148476-97-5)
- Apixaban Impurity 59 (CAS CATO-C4X-108859)
Recommended Standards
- Istradefylline Impurity 7 (CAS CATO-C4X-10617)
- Lercanidipine Impurity 2 (CAS CATO-C4X-13642)
- Istradefylline impurity 33 (CAS CATO-C4X-106133)
- Nimodipine Impurity 10 (CAS CATO-C4X-138510)
- Ezetimibe Impurity 117 (CAS 1013025-04-1)
- Nadifloxacin Impurity 6 (CAS 87-13-8)
- Carbocisteine Impurity 55 (CAS CATO-C4X-201055)
- (2-methoxyphenyl)methanethiol (CAS 874988-61-1)
- (S)-1-(4-(Trifluoromethoxy)phenyl)propan-2-ol (CAS 1198745-06-0)
- 5-(4-Bromophenyl)-4-(prop-2-en-1-yl)-4h-1,2,4-triazole-3-thiol (CAS 91813-57-9)
- 3-Bromo-4-fluoro-N-methylbenzenesulfonamide (CAS 1864395-88-9)
- 4-(2-Methylpiperidine-1-carboxamido)benzene-1-sulfonyl chloride (CAS 728864-65-1)
- 2-(Benzo[d]thiazol-2-ylamino)-5,6,7,8-tetrahydroquinazolin-4(3H)-one (CAS 371202-73-2)
- D-γ-Glu20-Side-Tirzepatide (CAS CATO-CPTD788929)
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