Roxadustat Impurity 86 CAS CATO-C4X-221386
| CAS No. | CATO-C4X-221386 |
| Molecular Formula | C18H19NO4 |
| Molecular Weight | 313.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Roxadustat Impurity 86 (C18H19NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Roxadustat Impurity 86 (CAS CATO-C4X-221386) is a certified pharmaceutical impurity reference standard with the molecular formula C18H19NO4 and a molecular weight of 313.35 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Roxadustat Impurity 86 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H19NO4 |
| Molecular Weight | 313.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Roxadustat Standards
- Roxadustat Impurity 57 (CAS 38791-58-1)
- Roxadustat Impurity 8 (CAS CATO-C4X-22138)
- Roxadustat Impurity 89 (CAS CATO-C4X-221389)
- Roxadustat Impurity 92 (CAS CATO-C4X-221392)
- Roxadustat Impurity N6 (CAS 1421312-32-4)
- Roxadustat Impurity 165 (CAS CATO-C4X-2213165)
- Roxadustat Impurity 22 (CAS CATO-C4X-221322)
- Roxadustat Impurity N1 (CAS 808116-52-1)
Recommended Standards
- Lumateperone impurity 55 (CAS CATO-C4X-220155)
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- Sulfadoxine-d3 (CAS 1262770-70-6)
- Ponatinib Impurity 58 (CAS CATO-C4X-226958)
- Calcitriol Impurity 64 (CAS CATO-C4X-151064)
- Levetiracetam Impurity 26 (CAS 20496-01-9)
- 3-((2,4-Difluorophenoxy)methyl)azetidine (CAS 954225-13-9)
- (E)-[(2-{[(4-chlorophenyl)methyl]sulfanyl}quinolin-3-yl)methylidene]amino 3-methylbenzoate (CAS 478079-35-5)
- 2-Bromo-N-cyclohexylbenzamide (CAS 159029-70-6)
- Polaprezinc Impurity N1 (CAS 46119-06-6 (free base))
- 4,4'-Methylenebis(3-methyl-1-phenyl-1H-pyrazol-5(4H)-one) (CAS 7149-40-8)
- 1,2-Dimethyl-6-oxo-1,6-dihydropyrimidine-5-carbonitrile (CAS 53135-29-8)
- D-Ile17-Tirzepatide (CAS CATO-CPTD788917)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com