Rivaroxaban impurity 189 CAS CATO-C4X-1090189
| CAS No. | CATO-C4X-1090189 |
| Molecular Formula | C13H19N3O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C13H19N3O3HCl, Rivaroxaban impurity 189 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 301.77 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Rivaroxaban impurity 189 (CAS CATO-C4X-1090189, C13H19N3O3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Rivaroxaban impurity 189 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H19N3O3 HCl |
| Molecular Weight | 301.77 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Rivaroxaban Standards
- Rivaroxaban Impurity 96 (CAS 1007650-38-5)
- Rivaroxaban Impurity 57 (CAS 1082495-22-4)
- Rivaroxaban Impurity 47 (CAS 1082588-73-5)
- Rivaroxaban-d4 (CAS 1132681-38-9)
- Rivaroxaban Impurity 74 (CAS 113471-08-2)
- Rivaroxaban EP Impurity I (CAS 1151893-81-0)
- Rivaroxaban 3-Hydroxy Metabolite (CAS 1159977-46-4)
- Rivaroxaban Impurity 15 (Mixture of Diastereomers) (CAS 1160169-99-2)
Recommended Standards
- Crisaborole Impurity 23 (CAS CATO-C4X-202123)
- Felbinac Impurity 3 (CAS 26140-60-3)
- Phenylbutyrate Impurity 14 (CAS 358349-85-6)
- Ethyl 2-((tert-butoxycarbonyl)amino)-2-(diethoxyphosphoryl)acetate (CAS 83027-00-3)
- 3-(Piperidin-2-yl)pyridine-2(1H)-thione (CAS 1270429-80-5)
- 1-{4-[(2E)-3-(2-Bromophenyl)prop-2-enoyl]phenyl}-1H-pyrrole-2,5-dione (CAS 1365988-73-3)
- (S)-2-((S)-2-(3-(Furan-2-yl)acrylamido)-3-phenylpropanamido)-4-methylpentanamide (CAS 110700-76-0)
- Desmopressin Impurity 29 (CAS CATO-C4X-221529)
- 2-Ethynyl-4-(trifluoromethyl)aniline (CAS 878133-02-9)
- Insulin Glargine Metabolite M2 (CAS CATO-CPTD788867)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com