Dronedarone Impurity 29 CAS CATO-C4X-109229

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-109229
Molecular FormulaC21H23NO7S2
Molecular Weight465.54 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Dronedarone Impurity 29 CAS CATO-C4X-109229 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 465.54 g/mol gives Dronedarone Impurity 29 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Dronedarone Impurity 29 (CAS CATO-C4X-109229) is a certified pharmaceutical impurity reference standard with the molecular formula C21H23NO7S2 and a molecular weight of 465.54 g/mol.

Dronedarone Impurity 29 (C21H23NO7S2) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H23NO7S2
Molecular Weight465.54 g/mol
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms1
Sulfur Atoms2

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