Ezetimibe Impurity 117 CAS CATO-C4X-1098117
| CAS No. | CATO-C4X-1098117 |
| Molecular Formula | C27H24FNO5 |
| Molecular Weight | 461.48 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ezetimibe Impurity 117 (C27H24FNO5) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Ezetimibe Impurity 117 (CAS CATO-C4X-1098117), a pharmacopoeial impurity reference standard (molecular formula C27H24FNO5, MW 461.48 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H24FNO5 |
| Molecular Weight | 461.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ezetimibe Standards
- Ezetimibe Impurity 130 (CAS CATO-C4X-1098130)
- Ezetimibe Impurity 99 (CAS CATO-C4X-109899)
- Ezetimibe Impurity 122 (CAS CATO-C4X-1098122)
- Ezetimibe Impurity 49 (CAS 1044664-24-5)
- Ezetimibe Impurity 1 Sodium salt (CAS 1400989-75-4)
- Ezetimibe Impurity S (CAS 190448-46-5)
- Ezetimibe Impurity 6 (CAS CATO-C4X-10986)
- Ezetimibe Impurity 7 (CAS CATO-C4X-10987)
Recommended Standards
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- Perindopril Impurity N4 (CAS 145513-54-8)
- Paliperidone Impurity 104 (CAS CATO-C4X-1724104)
- Atropine Impurity 48 (CAS 3423-23-2)
- N-{2-Cyano-5-[(cyanomethyl)sulfanyl]-4-phenyl-3-thienyl}-4-methylbenzenecarboxamide (CAS 860609-94-5)
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- 1-Tert-butyl-1h-pyrrole-2-carbaldehyde (CAS 23373-78-6)
- 1h-Indazole-4-carboxamide (CAS 1203579-36-5)
- Pyrroloquinoline quinone (CAS 72909-34-3)
- Peptide Impurity 06 (CAS CATO-CPTD788806)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com