Ezetimibe Impurity S CAS 190448-46-5
| CAS No. | 190448-46-5 |
| Molecular Formula | C26H23F2NO4 |
| Molecular Weight | 451.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Ezetimibe Impurity S (C26H23F2NO4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 451.46 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Ezetimibe Impurity S (CAS 190448-46-5), molecular formula C26H23F2NO4 and molecular weight 451.46 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ezetimibe Impurity S meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H23F2NO4 |
| Molecular Weight | 451.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ezetimibe Standards
- Ezetimibe Impurity 49 (CAS 1044664-24-5)
- Ezetimibe Impurity 1 Sodium salt (CAS 1400989-75-4)
- Ezetimibe Impurity 122 (CAS CATO-C4X-1098122)
- Ezetimibe Impurity 130 (CAS CATO-C4X-1098130)
- Ezetimibe Impurity 99 (CAS CATO-C4X-109899)
- Ezetimibe Impurity 117 (CAS CATO-C4X-1098117)
- Ezetimibe Impurity 109 (CAS CATO-C4X-1098109)
- Ezetimibe Impurity 129 (CAS CATO-C4X-1098129)
Recommended Standards
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- Cefuroxime Impurity 58 (CAS CATO-C4X-124558)
- 2-((3-Isobutyl-4-oxo-3,4-dihydroquinazolin-2-yl)thio)-N-(4-(trifluoromethoxy)phenyl)acetamide (CAS 882083-32-1)
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- 1-(thien-3-ylmethyl)piperazine,2HCL (CAS 130288-91-4)
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- N-(3,4-dimethoxyphenethyl)pentan-3-amine hydrobromide (CAS 1609404-31-0)
- 2-(2-((2,6-Dichloro-4-methoxyphenyl)amino)phenyl-d (CAS 1382084-37-8)
- 2-((1H-Imidazol-1-yl)methyl)benzoic acid (CAS 883543-82-6)
- 1,5-Dichloro-3-fluoro-2-(trifluoromethylthio)benzene (CAS 1806281-50-4)
- Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 2022956-56-3)
Why CATO?
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