Ezetimibe Impurity 65 CAS CATO-C4X-109865
| CAS No. | CATO-C4X-109865 |
| Molecular Formula | C27H29F2NO3Si |
| Molecular Weight | 481.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ezetimibe Impurity 65 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Ezetimibe Impurity 65 (CAS CATO-C4X-109865), a pharmacopoeial impurity reference standard (molecular formula C27H29F2NO3Si, MW 481.61 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Ezetimibe Impurity 65 (C27H29F2NO3Si) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 481.61 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C27H29F2NO3Si |
| Molecular Weight | 481.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ezetimibe Standards
- Ezetimibe Impurity 64 (CAS CATO-C4X-109864)
- Ezetimibe Impurity 57 (CAS CATO-C4X-109857)
- Ezetimibe Impurity C115 (CAS 204589-96-8)
- Ezetimibe Impurity 6 (CAS CATO-C4X-10986)
- Ezetimibe Impurity 7 (CAS CATO-C4X-10987)
- Ezetimibe diacetate (CAS 163380-20-9)
- Ezetimibe Impurity 12(Intermediate Isomer Impurity) (CAS CATO-C4X-109812)
- Ezetimibe Impurity 8 (CAS CATO-C4X-10988)
Recommended Standards
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- Glycerol Impurity 30 (CAS 106182-18-7)
- Olumacostat Glasaretil (CAS 1261491-89-7)
- Glycerol Impurity 29 (CAS 51827-57-7)
- Tolvaptan Impurity 18 (CAS 2486-75-1)
- Maprotiline EP impurity C HCl (CAS 92202-51-2)
- Relugolix Impurity 184 (CAS CATO-C4X-2429184)
- 4-Methyl-2-((tert-pentylamino)methyl)phenol (CAS 1342501-65-8)
- 5-[(2S)-1-methylpyrrolidin-2-yl]pyridin-2-amine (CAS 22790-82-5)
- 2-Amino-2-(2-phenylthiazol-4-yl)acetic acid (CAS 1566590-29-1)
- (2Z)-2-Cyano-3-{[(pyridin-4-yl)methyl]amino}but-2-enamide (CAS 303153-02-8)
- 2-(1-Methyl-1h-pyrazol-4-yl)-1,3-thiazole-5-carbaldehyde (CAS 1248209-05-3)
- Aripiprazole Impurity 58 (CAS 1424857-63-5)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com