Alogliptin Impurity 72 CAS CATO-C4X-109972
| CAS No. | CATO-C4X-109972 |
| Molecular Formula | C18H21N5O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Alogliptin Impurity 72 (CAS CATO-C4X-109972, C18H21N5O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Alogliptin Impurity 72 (C18H21N5O2HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Alogliptin Impurity 72 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H21N5O2 HCl |
| Molecular Weight | 375.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Alogliptin Standards
- Alogliptin Impurity 3 (CAS 1108731-49-2)
- Alogliptin Impurity 89 (CAS 1108732-05-3)
- Alogliptin impurity 77 HCl (CAS 1108732-05-3（free base）)
- Alogliptin Impurity 51 (CAS 1133421-35-8)
- Alogliptin Impurity 38 (CAS 120977-94-8)
- Alogliptin Impurity 16 (CAS 1217476-03-3)
- Alogliptin Impurity 33 (CAS 123-56-8)
- Alogliptin Impurity 69 (CAS 1243378-31-5)
Recommended Standards
- Tadalafil Impurity 141 (CAS 477970-21-1)
- Ibrutinib Impurity 5 (CAS 1987905-93-0)
- Vitamin A Impurity 31 (CAS CATO-C4X-218731)
- (R)-4-methylmorpholine-3-carboxylic acid (CAS 1821837-71-1)
- Ethyl 4-((4-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl)amino)-4-oxobutanoate (CAS 1226455-96-4)
- 2-((4-Bromobenzyl)thio)-5-methyl-1,3,4-thiadiazole (CAS 42755-33-9)
- n-Heptyl 4-hydroxybenzoate-d4 (CAS CATO-CCFD201108)
- 4-Fluoro-2-(phenylethynyl)aniline (CAS 875930-15-7)
- Pefloxacin Impurity 8 (CAS CATO-C4X-23338)
- Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com