Linagliptin Impurity 26 CAS CATO-C4X-110126
| CAS No. | CATO-C4X-110126 |
| Molecular Formula | C20H28N4O2 |
| Molecular Weight | 356.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Linagliptin Impurity 26 (CAS CATO-C4X-110126, C20H28N4O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Linagliptin Impurity 26 (C20H28N4O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Linagliptin Impurity 26 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H28N4O2 |
| Molecular Weight | 356.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Linagliptin Standards
- Linagliptin impurity 99 (CAS CATO-C4X-110199)
- Linagliptin Impurity 1 (CAS CATO-C4X-11011)
- Linagliptin Impurity 83 (CAS 2436762-89-7)
- Linagliptin impurity 97 (CAS CATO-C4X-110197)
- Linagliptin Impurity 3 (CAS CATO-C4X-11013)
- Linagliptin impurity 151 (CAS CATO-C4X-1101151)
- Linagliptin Impurity 29 (CAS 1911621-52-7)
- Linagliptin impurity 118 (CAS CATO-C4X-1101118)
Recommended Standards
- Ceritinib Impurity 16 (CAS CATO-C4X-1048916)
- Dexamethasone EP Impurity E (CAS 13209-41-1)
- Mirabegron Impurity 1 (CAS 223673-36-7)
- Betamethasone EP Impurity C (CAS 13504-15-9)
- Berberine Impurity 30 (CAS 2648606-63-5)
- Fudosteine Impurity 19 HCl (CAS CATO-C4X-144719)
- Ceftolozane Impurity 41 (CAS CATO-C4X-240641)
- 5-Chloro-3-(chlorosulfonyl)-2-methylbenzoic acid (CAS 1423028-58-3)
- 3'-Fluoro-4'-methyl-[1,1'-biphenyl]-3-carboxylic acid (CAS 885964-56-7)
- 3-(5-Formyl-1,2,4-oxadiazol-3-yl)benzonitrile (CAS 944906-23-4)
- 2-[3-(methylcarbamoyl)phenoxy]acetic acid (CAS 1018600-26-4)
- 1-(4-Chlorophenyl)-3-(2,4-dimethylphenyl)propan-1-one (CAS 898793-93-6)
- 4-Fluoro-2,3-dimethoxybenzaldehyde (CAS 1364687-90-0)
- Liraglutide (14-31)TFA Salt (CAS CATO-C4X-19927)
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