Dexamethasone EP Impurity E CAS 13209-41-1
| CAS No. | 13209-41-1 |
| Molecular Formula | C22H28O4 |
| Molecular Weight | 356.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Dexamethasone EP Impurity E (C22H28O4) contains a flavonoid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 356.46 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a process- or degradation-related impurity, Dexamethasone EP Impurity E (CAS 13209-41-1, C22H28O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dexamethasone EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H28O4 |
| Molecular Weight | 356.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
Related Dexamethasone Standards
- Dexamethasone EP Impurity K (CAS 1809224-82-5)
- Dexamethasone Impurity 94 (CAS 59861-00-6)
- Dexamethasone Impurity 33 (CAS 75262-69-0)
- Dexamethasone impurity 89 (CAS CATO-C4X-116589)
- Dexamethasone Impurity 59 (CAS CATO-C4X-116559)
- Dexamethasone Impurity 85 (CAS CATO-C4X-116585)
- Dexamethasone Impurity 58 (CAS CATO-C4X-116558)
- Dexamethasone EP Impurity J (CAS 2036-77-3)
Recommended Standards
- Linagliptin Impurity 26 (CAS CATO-C4X-110126)
- Betamethasone EP Impurity C (CAS 13504-15-9)
- Ceritinib Impurity 16 (CAS CATO-C4X-1048916)
- Betamethasone EP Impurity F (CAS 330157-04-5)
- Apixaban Impurity 128 (CAS CATO-C4X-1088128)
- Bosutinib Impurity 2 (CAS CATO-C4X-18472)
- Iguratimod Impurity 40 (CAS 1179354-65-4)
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- 2,2-Difluoro-2-(6-methoxypyridin-3-yl)acetic acid (CAS 2008444-82-2)
- 3-(4-aminophenoxy)propanoic acid (CAS 350699-65-9)
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- 4-Hydroxy-3-methoxy-N-methylbenzamide (CAS 60515-31-3)
- 95633-27-5 7-Azido-4-methylcoumarin MFCD16652405 7-Azido-4-methyl-1-benzopyran-2-one / AzMC (CAS 95633-27-5)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com