Palonosetron Impurity 32 HCl CAS CATO-C4X-110532
| CAS No. | CATO-C4X-110532 |
| Molecular Formula | C18H24N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Palonosetron Impurity 32 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Palonosetron Impurity 32 HCl (CAS CATO-C4X-110532), a pharmacopoeial impurity reference standard (molecular formula C18H24N2OHCl, MW 320.86 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Palonosetron Impurity 32 HCl (C18H24N2OHCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H24N2O HCl |
| Molecular Weight | 320.86 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Palonosetron Standards
- Palonosetron USP Related Compound B (CAS 1021456-82-5)
- Palonosetron Impurity 7 (CAS 120570-05-0)
- Palonosetron Impurity 34 (CAS 1227162-74-4)
- Palonosetron USP Related Compound E HCl (CAS 135729-55-4)
- Palonosetron-3-ene (CAS 135729-56-5)
- Palonosetron (CAS 135729-61-2)
- Palonosetron Hydrochloride (CAS 135729-62-3)
- Palonosetron Impurity N64 (CAS 135729-66-7)
Recommended Standards
- Finerenone Impurity 44 (CAS CATO-C4X-288044)
- Carfilzomib Impurity 32 (CAS CATO-C4X-102232)
- Etrasimod impurity 16 (CAS CATO-C4X-321416)
- 1-(Cyclobutylmethyl)-1H-pyrazol-5-amine (CAS 1448854-94-1)
- 1-(3,4-Dimethylphenyl)-4-hydrazinylphthalazine (CAS 304863-83-0)
- 4-(4-Methoxyphenyl)-5-(pyridin-2-yl)-4h-1,2,4-triazole-3-thiol (CAS 63279-73-2)
- 2-(4-Bromophenyl)-1H-1,2,4-triazol-3(2H)-one (CAS 197074-69-4)
- 1-(2-Chloro-6-nitrophenyl)azepane (CAS 40832-89-1)
- Indoxacarb Impurity 3 (CAS 127296-24-6)
- Semaglutide impurity 96 (CAS CATO-C4X-222696)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com