Gefitinib Impurity 85 CAS CATO-C4X-111785
| CAS No. | CATO-C4X-111785 |
| Molecular Formula | C11H11NO2 |
| Molecular Weight | 189.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Gefitinib Impurity 85 (CAS CATO-C4X-111785, C11H11NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Gefitinib Impurity 85 (C11H11NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Gefitinib Impurity 85 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11NO2 |
| Molecular Weight | 189.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Gefitinib Standards
- Gefitinib Impurity 34 (CAS 194423-17-1)
- Gefitinib Impurity 4 (CAS 179688-52-9)
- Gefitinib Impurity 8 (CAS 379228-50-9)
- Gefitinib Impurity 28 (CAS 1379208-77-1)
- Gefitinib Impurity N18 (CAS 58749-47-6)
- Gefitinib Impurity 18 (CAS 50413-44-0)
- Gefitinib Impurity 45 (CAS 350-30-1)
- Gefitinib Impurity 46 (CAS 2106-49-2)
Recommended Standards
- Amlodipine Impurity 89 (CAS CATO-C4X-109589)
- Ivabradine Impurity 55 (CAS 35202-54-1)
- Levetiracetam Impurity 47 (CAS CATO-C4X-106747)
- Rabeprazole impurity 48 (CAS 92288-14-7)
- Baloxavir Impurity 105 (CAS CATO-C4X-2108105)
- Lifitegrast Impurity 153 (CAS CATO-C4X-2409153)
- Desmopressin Impurity 21 (CAS CATO-C4X-221521)
- 1-((4-Bromo-2-fluorophenyl)sulfonyl)piperazine (CAS 1839318-16-9)
- 1-Benzyl-5-oxopyrrolidine-3-carbonyl chloride (CAS 114368-05-7)
- (3-Methoxyphenyl)(5-(phenoxymethyl)-1H-1,2,4-triazol-3-yl)methanamine (CAS 1707585-84-9)
- 5-Bromo-6-iodo-7-isopropyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS 2773489-99-7)
- 1-Fluorocyclobutanecarboxylic Acid (CAS 202932-09-0)
- Entero-Hylambatin (CAS 198541-90-1)
- Semaglutide impurity 40 (CAS CATO-C4X-222640)
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