Gefitinib Impurity 28 CAS 1379208-77-1
| CAS No. | 1379208-77-1 |
| Molecular Formula | C8H6N2O4 |
| Molecular Weight | 194.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 194.14 g/mol gives Gefitinib Impurity 28 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Gefitinib Impurity 28 (CAS 1379208-77-1), a pharmacopoeial impurity reference standard (molecular formula C8H6N2O4, MW 194.14 g/mol) used for the identification and quantification of trace impurities in APIs.
Gefitinib Impurity 28 (C8H6N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Gefitinib Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6N2O4 |
| Molecular Weight | 194.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Gefitinib Standards
- Gefitinib Impurity 4 (CAS 179688-52-9)
- Gefitinib Impurity 8 (CAS 379228-50-9)
- Gefitinib Impurity N18 (CAS 58749-47-6)
- Gefitinib Impurity 18 (CAS 50413-44-0)
- Gefitinib Impurity 85 (CAS CATO-C4X-111785)
- Gefitinib Impurity 34 (CAS 194423-17-1)
- Gefitinib Impurity 92 (CAS CATO-C4X-111792)
- Gefitinib Impurity 45 (CAS 350-30-1)
Recommended Standards
- 2-(Benzo[d][1,3]dioxol-5-yl)-2-oxoacetic acid (CAS 62396-98-9)
- Ascorbic Acid EP Impurity C (CAS 526-98-7)
- 5-ketogluconic acid (CAS 815-89-4)
- (3R,4S,5R)-Ascorbic Acid EP Impurity C (CAS 21675-47-8)
- Letermovir Impurity 104 (CAS CATO-C4X-2915104)
- Upadacitinib Impurity 147 (CAS CATO-C4X-2405147)
- Pramipexole Impurity 42 (CAS 1797134-75-8)
- Desmethyl Hydroxy Cerivastatin Sodium Salt (CAS 201793-00-2)
- 7-Hydroxy-2,4-dimethylquinoline-8-carboxylic acid (CAS 91569-72-1)
- Benzenamine, 4,4′-(21H,23H-porphine-5,15-diyl)bis- (CAS 292145-34-7)
- Articaine EP Impurity H HCl (CAS 2602451-77-2)
- 3-(4-Nitrophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine (CAS 1245773-13-0)
- 5-Fluorofuran-2-carbonyl Chloride (CAS 1173834-52-0)
- Palmitoyl hexapeptide-6 (CAS 891498-01-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com