Avanafil Impurity 159 CAS CATO-C4X-1118159

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-1118159
Molecular FormulaC23H30ClN5O4
Molecular Weight475.97 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Avanafil Impurity 159 CAS CATO-C4X-1118159 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 475.97 g/mol gives Avanafil Impurity 159 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Avanafil Impurity 159 (CAS CATO-C4X-1118159), a pharmacopoeial impurity reference standard (molecular formula C23H30ClN5O4, MW 475.97 g/mol) used for the identification and quantification of trace impurities in APIs.

Avanafil Impurity 159 (C23H30ClN5O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC23H30ClN5O4
Molecular Weight475.97 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity≥95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl-containing
Nitrogen Atoms5

Related Avanafil Standards

Recommended Standards

Why CATO?