Avanafil Impurity 28 CAS CATO-C4X-111828
| CAS No. | CATO-C4X-111828 |
| Molecular Formula | C28H30ClN9O3 |
| Molecular Weight | 576.05 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 576.05 g/mol gives Avanafil Impurity 28 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Avanafil Impurity 28 (CAS CATO-C4X-111828) is a certified pharmaceutical impurity reference standard with the molecular formula C28H30ClN9O3 and a molecular weight of 576.05 g/mol.
Avanafil Impurity 28 (C28H30ClN9O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H30ClN9O3 |
| Molecular Weight | 576.05 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 9 |
Related Avanafil Standards
- Avanafil Impurity 119 (CAS CATO-C4X-1118119)
- Avanafil Impurity 156 (CAS CATO-C4X-1118156)
- Avanafil Impurity 144 (CAS CATO-C4X-1118144)
- Avanafil Impurity 158 (CAS CATO-C4X-1118158)
- Avanafil Impurity 39 (CAS CATO-C4X-111839)
- Avanafil Impurity 157 (CAS CATO-C4X-1118157)
- Avanafil Impurity 59 (CAS 372117-51-6)
- Avanafil Impurity 150 (CAS CATO-C4X-1118150)
Recommended Standards
- Pigment Blue 15 (CAS 147-14-8)
- ((2-Butyl-4-chloro-1-((2`-(1-nitroso-1H-tetrazol-5-yl)-[1,1`-biphenyl]-4-yl)methyl)-1H-imidazole-5-yl)methonol) (CAS CATO-C3D-26203)
- Meclizine Impurity 14 (CAS 299460-62-1)
- Tegoprazan Impurity 29 (CAS CATO-C4X-229729)
- Vonoprazan Impurity 16 (CAS 16133-25-8)
- Propofol Impurity 50 (CAS CATO-C4X-147350)
- Valsartan Impurity 125 (CAS 1894176-40-9)
- 1-((5-(Hydroxy(thiophen-2-yl)methyl)thiophen-2-yl)methyl)-3-phenylurea (CAS 1421509-24-1)
- 5-Bromo-N-ethylpyrimidin-2-amine, 97% (CAS 4214-67-9)
- Benzo[b][1,10]phenanthrolin-7-amine (CAS 24902-11-2)
- 4-Bromo-2-(dimethylphosphoryl)benzonitrile (CAS 2287315-21-1)
- N-(2-Methoxyphenyl)-2-(4-methoxyphenyl)quinoline-4-carboxamide (CAS 332157-18-3)
- 5-Methyl-1-(pyridin-4-ylmethyl)-1h-1,2,3-triazole-4-carboxylic acid (CAS 1248975-23-6)
- [γ-Glu]15 Semaglutide (CAS CATO-C4X-222690)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com