Valsartan Impurity 125 CAS 1894176-40-9
| CAS No. | 1894176-40-9 |
| Molecular Formula | C25H31N5O3 |
| Molecular Weight | 449.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Valsartan Impurity 125 (CAS 1894176-40-9), a pharmacopoeial impurity reference standard (molecular formula C25H31N5O3, MW 449.55 g/mol) used for the identification and quantification of trace impurities in APIs.
Valsartan Impurity 125 (C25H31N5O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Valsartan Impurity 125 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H31N5O3 |
| Molecular Weight | 449.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 5 |
Related Valsartan Standards
- Valsartan Impurity 106 (CAS CATO-C4X-1057106)
- Valsartan Impurity 112 (CAS CATO-C4X-1057112)
- Valsartan Impurity 120 (CAS 137863-48-0)
- Valsartan USP Related Compound E (CAS 137863-17-3)
- Valsartan Impurity 73 (CAS CATO-C4X-105773)
- Valsartan Impurity 74 (CAS CATO-C4X-105774)
- Valsartan Impurity 75 (CAS CATO-C4X-105775)
- Valsartan Impurity 76 (CAS CATO-C4X-105776)
Recommended Standards
- CAS CATO-C3D-4200 (CAS CATO-C3D-4200)
- ICA-121431, >98% (HPLC) (CAS 313254-51-2)
- Cholesteryl Bromide (CAS 516-91-6)
- Valsartan Impurity 77 (CAS CATO-C4X-105777)
- Droperidol Impurity 8 (CAS 4644-61-5)
- Cholecalciferol Impurity 33 (CAS CATO-C4X-158633)
- Trametinib impurity 26 (CAS CATO-C4X-27826)
- 2-Amino-6-fluorobenzenethiol (CAS 100493-32-1)
- N-(7,10-dimethyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]oxazepin-2-yl)-4-methoxybenzamide (CAS 866152-13-8)
- (2-Bromo-1-(cyclohexyloxy)ethyl)benzene (CAS 1249758-51-7)
- N-(3-(1H-Imidazol-1-yl)propyl)-4-chloro-3-ethoxybenzenesulfonamide (CAS 873671-64-8)
- 2-Bromo-6-methylisonicotinic acid (CAS 25462-84-4)
- 2-(4-((5-Bromothiophen-3-yl)methyl)piperazin-1-yl)ethan-1-ol (CAS 1248743-98-7)
- Fibrinopeptide B (human) (CAS 36204-23-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com