Avanafil Impurity 33 CAS CATO-C4X-111833
| CAS No. | CATO-C4X-111833 |
| Molecular Formula | C16H18ClN3O3S |
| Molecular Weight | 367.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Avanafil Impurity 33 (CAS CATO-C4X-111833), a pharmacopoeial impurity reference standard (molecular formula C16H18ClN3O3S, MW 367.85 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C16H18ClN3O3S, Avanafil Impurity 33 contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 367.85 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H18ClN3O3S |
| Molecular Weight | 367.85 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Avanafil Standards
- Avanafil Impurity 43 (CAS 330785-81-4)
- Avanafil Impurity 56 (CAS 2310299-29-5)
- Avanafil Impurity 112 (CAS CATO-C4X-1118112)
- Avanafil Impurity 20 (CAS 2250242-42-1)
- Avanafil Impurity 68 (CAS 2250243-09-3)
- Avanafil Impurity 90 (CAS 2250242-49-8)
- Avanafil Impurity 52 (CAS CATO-C4X-111852)
- Avanafil Impurity 37 (CAS CATO-C4X-111837)
Recommended Standards
- N-(4-chlorophenyl)-3-methyl-1-phenyl-1H-thieno[2,3-c]pyrazole-5-carboxamide (CAS 296262-27-6)
- N-(4-chlorophenyl)-2-hydroxy-2-methyl-3-tosylpropanamide (CAS 338424-24-1)
- Dasatinib impurity 67 (CAS 302964-06-3)
- Methyl N-(5-chloro-2-methylphenyl)-N-tosylglycinate (CAS 333453-15-9)
- Doxycycline Impurity 23 (CAS CATO-C4X-193123)
- Ornidazole Impurity 3 (CAS 16773-52-7)
- Oseltamivir impurity 184 (CAS CATO-C4X-1720184)
- Diethyl 1,4-Dihydro-2,6-Dimethyl-3,5-Pyridinedicarboxylate (CAS 1149-23-1)
- tert-Butyl (5-bromobenzo[d][1,3]dioxol-4-yl)carbamate (CAS 401811-77-6)
- 5-Amino-1-indanone (CAS 3470-54-0)
- 5-Bromo-4-phenylthiazol-2-amine hydrobromide (CAS 113511-22-1)
- 4-(4-phenyl-1,3-thiazol-2-yl)morpholine (CAS 19983-28-9)
- Azido-PEG5-CH2CO2H (CAS 217180-81-9)
- Tau Peptide (337-368) (Repeat 4 Domain) trifluoroacetate salt (CAS 330456-27-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com