Avanafil Impurity 112 CAS CATO-C4X-1118112
| CAS No. | CATO-C4X-1118112 |
| Molecular Formula | C18H19ClN4O3 |
| Molecular Weight | 374.82 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Avanafil Impurity 112 (CAS CATO-C4X-1118112), a pharmacopoeial impurity reference standard (molecular formula C18H19ClN4O3, MW 374.82 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Avanafil Impurity 112 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 374.82 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Avanafil Impurity 112 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H19ClN4O3 |
| Molecular Weight | 374.82 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Avanafil Standards
- Avanafil Impurity 56 (CAS 2310299-29-5)
- Avanafil Impurity 52 (CAS CATO-C4X-111852)
- Avanafil Impurity 33 (CAS CATO-C4X-111833)
- Avanafil Impurity 43 (CAS 330785-81-4)
- Avanafil Impurity 79 (CAS 330785-82-5)
- Avanafil Impurity 19 (CAS 2250242-12-5)
- Avanafil Impurity 88 (CAS 2250243-52-6)
- Avanafil Impurity 20 (CAS 2250242-42-1)
Recommended Standards
- N-(5-chloro-2-(4-methylpiperazin-1-yl)phenyl)-3-nitrobenzamide (CAS 383146-65-4)
- Sildenafil Impurity 278 (CAS CATO-C4X-1128278)
- N-(4-Chlorophenyl)-1-oxo-2-phenyl-1,2-dihydroisoquinoline-4-carboxamide (CAS 477850-82-1)
- Chlorophacinone (CAS 3691-35-8)
- Benidipine Impurity 35 (CAS 814916-95-5)
- Avatrombopag Impurity 128 (CAS CATO-C4X-2234128)
- Glucose impurity 24 (CAS 30517-76-1)
- 3-Amino-5-fluoro-2-methylbenzamide (CAS 1378802-64-2)
- Phosphoric acid, hexyl ester, potassium salt (CAS 37242-45-8)
- Ethyl 2-(5-(chloromethyl)-1,2,4-oxadiazol-3-yl)acetate (CAS 1208081-49-5)
- Rac-(1S,5S)-6-azabicyclo[3.2.0]heptane (CAS 1821759-34-5)
- Mesitylmethanethiol (CAS 21411-42-7)
- 2-(Methoxymethyl)-6-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2760431-26-1)
- Ginseng Tetrapeptide (CAS 178553-95-2)
Why CATO?
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