Sitagliptin Impurity 68 CAS CATO-C4X-114468
| CAS No. | CATO-C4X-114468 |
| Molecular Formula | C16H13F5N4O2 |
| Molecular Weight | 388.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Sitagliptin Impurity 68 (C16H13F5N4O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Sitagliptin Impurity 68 (CAS CATO-C4X-114468), a pharmacopoeial impurity reference standard (molecular formula C16H13F5N4O2, MW 388.29 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Sitagliptin Impurity 68 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H13F5N4O2 |
| Molecular Weight | 388.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Sitagliptin Standards
- Sitagliptin Impurity 69 (CAS CATO-C4X-114469)
- Sitagliptin Impurity 105 (CAS CATO-C4X-1144105)
- Sitagliptin Impurity 75 (CAS 1334244-24-4)
- Sitagliptin Impurity 151 (CAS 1334244-32-4)
- Sitagliptin Impurity 152 (CAS CATO-C4X-1144152)
- Sitagliptin EP Impurity C (CAS 945261-48-3)
- Sitagliptin EP Impurity B (CAS 486460-31-5)
- Sitagliptin Impurity 99 (CAS 486459-88-5)
Recommended Standards
- Phenoxathiine 10,10-dioxide (CAS 950-47-0)
- Perfluorophenyl 4-((tetrahydro-2H-pyran-4-yl)oxy)benzoate (CAS 930110-97-7)
- Carboplatin Impurity 11 (CAS CATO-C4X-206111)
- Pentafluorophenyl 2-(tetrahydro-2H-pyran-4-yloxy)benzoate (CAS 926921-58-6)
- Tranexamic Acid EP Impurity F (CAS 1599413-49-6)
- Trelagliptin Impurity 49 (CAS CATO-C4X-104649)
- Axitinib Impurity N1 (CAS 1420478-90-5)
- 2,3,5-Trichloroaniline (CAS 18487-39-3)
- 5-Oxopyrrolidine-1,2-dicarboxylic acid (CAS 98109-83-2)
- Methyl imidazo[1,2-a]pyrazine-6-carboxylate (CAS 1448536-57-9)
- Nonafluorovaleryl Fluoride (CAS 375-62-2)
- 1-(4-Hydroxy-7-(p-tolyl)thieno[3,2-d]pyrimidin-2-yl)piperidine-3-carboxylic acid (CAS 1243102-02-4)
- Selegiline Impurity 8 (CAS CATO-C4X-19168)
- D-[Val]10-Semaglutide (CAS CATO-CPTD788630)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com