Ivabradine impurity 77 CAS CATO-C4X-111977
| CAS No. | CATO-C4X-111977 |
| Molecular Formula | C26H34N2O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Ivabradine impurity 77 (CAS CATO-C4X-111977, C26H34N2O5HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C26H34N2O5HCl, Ivabradine impurity 77 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 491.03 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Ivabradine impurity 77 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H34N2O5 HCl |
| Molecular Weight | 491.03 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ivabradine Standards
- Ivabradine Impurity 25 HCl (CAS 1132079-01-6)
- Ivabradine impurity 90 (CAS 1132667-04-9)
- Ivabradine Impurity 9 (CAS 1204612-29-2)
- Ivabradine Impurity 28 (CAS 1206230-28-5)
- Ivabradine-d3 Hydrochloride (CAS 1217809-61-4)
- Ivabradine impurity 86 (CAS 1220993-44-1)
- Ivabradine Impurity 20 (CAS 1235547-06-4)
- Ivabradine Impurity 21 (CAS 1235547-07-5)
Recommended Standards
- Relugolix Impurity 86 (CAS CATO-C4X-242986)
- Tandospirone Impurity 58(Lurasidone Impurity) (CAS 27862-85-7)
- Cefpirome Impurity 8 (CAS 533-37-9)
- Cilastatin Impurity 44 (CAS CATO-C4X-196044)
- Ethyl 2-amino-2-(5-methylpyridin-2-yl)acetate (CAS 500993-08-8)
- 1-(3,4-Dimethylphenyl)-6-oxopiperidine-3-carboxylic acid (CAS 1275803-36-5)
- 3-[6-(hydroxymethyl)pyridin-2-yl]cyclohex-2-en-1-one (CAS 1803562-64-2)
- 4-Chloro-6-((2-methylcyclohexyl)oxy)pyrimidine (CAS 405931-07-9)
- 4-(Benzyloxy)-5-bromobenzene-1,2-diamine (CAS 1373232-38-2)
- Autocamtide-2-Related Inhibitory Peptide TFA (CAS 167114-91-2（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com